Medicinal attributes of 1, 2, 3-triazoles: Current developments
Triazoles are important five-membered heterocyclic scaffold due to their extensive biological
activities. This framework can be readily obtained in good to excellent yields on the …
activities. This framework can be readily obtained in good to excellent yields on the …
Beyond click chemistry–supramolecular interactions of 1, 2, 3-triazoles
B Schulze, US Schubert - Chemical Society Reviews, 2014 - pubs.rsc.org
The research on 1, 2, 3-triazoles has been lively and ever-growing since its stimulation by
the advent of click chemistry. The attractiveness of 1H-1, 2, 3-triazoles and their derivatives …
the advent of click chemistry. The attractiveness of 1H-1, 2, 3-triazoles and their derivatives …
Versatile synthetic platform for 1, 2, 3-triazole chemistry
1, 2, 3-Triazole scaffolds are not obtained in nature, but they are still intensely investigated
by synthetic chemists in various fields due to their excellent properties and green synthetic …
by synthetic chemists in various fields due to their excellent properties and green synthetic …
New click-chemistry methods for 1, 2, 3-triazoles synthesis: Recent advances and applications
J Totobenazara, AJ Burke - Tetrahedron letters, 2015 - Elsevier
Triazoles find applications in several major technological areas, and especially in drug
discovery. The click-chemistry approaches based on Huisgen's cycloaddition reaction are …
discovery. The click-chemistry approaches based on Huisgen's cycloaddition reaction are …
p-Toluenesulfonic Acid Mediated 1,3-Dipolar Cycloaddition of Nitroolefins with NaN3 for Synthesis of 4-Aryl-NH-1,2,3-triazoles
XJ Quan, ZH Ren, YY Wang, ZH Guan - Organic letters, 2014 - ACS Publications
A p-TsOH-mediated 1, 3-dipolar cycloaddition of nitroolefins and sodium azide for the
synthesis of 4-aryl-NH-1, 2, 3-triazoles has been developed. p-TsOH was discovered as a …
synthesis of 4-aryl-NH-1, 2, 3-triazoles has been developed. p-TsOH was discovered as a …
An Organocatalytic Azide–Aldehyde [3+ 2] Cycloaddition: High‐Yielding Regioselective Synthesis of 1, 4‐Disubstituted 1, 2, 3‐Triazoles
DB Ramachary, AB Shashank… - Angewandte Chemie …, 2014 - Wiley Online Library
Abstract An organocatalytic azide–aldehyde [3+ 2] cycloaddition (organo‐click) reaction of a
variety of enolizable aldehydes is reported. The organo‐click reaction is characterized by a …
variety of enolizable aldehydes is reported. The organo‐click reaction is characterized by a …
A Metal‐Free Three‐Component Reaction for the Regioselective Synthesis of 1, 4, 5‐Trisubstituted 1, 2, 3‐Triazoles
A metal‐free three‐component reaction to synthesize 1, 4, 5‐trisubstituted 1, 2, 3‐triazoles
from readily available building blocks, such as aldehydes, nitroalkanes, and organic azides …
from readily available building blocks, such as aldehydes, nitroalkanes, and organic azides …
Ramachary-Bressy-Wang [3+ 2] cycloaddition reaction: Synthesis of fully decorated 1, 2, 3-triazoles as potent anticancer and EGFR inhibitors
M Kumar, SK Nukala, NS Thirukovela… - Journal of Molecular …, 2022 - Elsevier
A general strategy was developed for the synthesis of new fully decorated 1, 2, 3-triazoles
(5a-m & 6a-e) containing coumarine and sulfonyl-benzimidazole from 3-(2-((1-methyl-1H …
(5a-m & 6a-e) containing coumarine and sulfonyl-benzimidazole from 3-(2-((1-methyl-1H …
Regioselective synthesis of multisubstituted 1, 2, 3-triazoles: moving beyond the copper-catalyzed azide–alkyne cycloaddition
F Wei, W Wang, Y Ma, CH Tung, Z Xu - Chemical Communications, 2016 - pubs.rsc.org
Copper (I)-catalyzed azide–alkyne cycloaddition (CuAAC) is an essential “click chemistry”
reaction that is widely used in chemical biology, medicinal chemistry and materials science …
reaction that is widely used in chemical biology, medicinal chemistry and materials science …
Organocatalytic routes toward substituted 1, 2, 3-triazoles
The present feature article describes the different organocatalytic routes for the synthesis of
substituted 1, 2, 3-triazoles. This methodology has recently gained much attention due to its …
substituted 1, 2, 3-triazoles. This methodology has recently gained much attention due to its …