The pathogenesis of dengue virus infection is attributed to complex interplay between virus,
host genes and host immune response. Host factors such as antibody-dependent …

The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …

Dengue viruses have spread rapidly within countries and across regions in the past few
decades, resulting in an increased frequency of epidemics and severe dengue disease …

Vector-borne diseases are transmitted by haematophagous arthropods (for example,
mosquitoes, ticks and sandflies) to humans and wild and domestic animals, with the largest …

Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …

Coronaviruses (CoVs) are large enveloped non-segmented positive-strand RNA viruses that
broadly distribute among humans and other animal species, including bats, mice and birds …

The enzyme Dicer is best known for its role as a riboendonuclease in the small RNA
pathway. In this canonical role, Dicer is a critical regulator of the biogenesis of microRNA …

Organisms throughout biology need to maintain the integrity of their genome. From bacteria
to vertebrates, life has established sophisticated mechanisms to detect and eliminate foreign …

RNA interference (RNAi), the sequence-specific suppression of gene expression, offers
great opportunities for insect science, especially to analyze gene function, manage pest …

The outbreak of Zika virus (ZIKV) and associated fetal microcephaly mandates efforts to
understand the molecular processes of infection. Related flaviviruses produce noncoding …