Practical advice for determining the role of BCR‐ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia

E Jabbour, S Branford, G Saglio, D Jones, JE Cortes… - Cancer, 2011 - Wiley Online Library
Data demonstrating the superiority of nilotinib over imatinib in the frontline treatment of
chronic myeloid leukemia (CML) and ongoing studies with dasatinib and bosutinib are …

Abl tyrosine kinase inhibitors for overriding Bcr–Abl/T315I: from the second to third generation

R Tanaka, S Kimura - Expert review of anticancer therapy, 2008 - Taylor & Francis
Treatment of chronic myeloid leukemia (CML) has changed drastically with the emergence
of the Abl tyrosine kinase inhibitor (TKI), imatinib mesylate. However, primary and secondary …

BCR-ABL1-positive CML and BCR-ABL1-negative chronic myeloproliferative disorders: some common and contrasting features

NCP Cross, GQ Daley, AR Green, TP Hughes… - Leukemia, 2008 - nature.com
Introduction 'yyto put together such apparently dissimilar diseases as chronic granulocytic
leukaemia, polycythemia, myeloid metaplasia and di Guglielmo's syndrome may …

Synthesis of 8-aminoquinolines as inhibitors of tyrosine kinases

E Rosso - 2010 - dspace.unive.it
Chronic myelogenous leukemia (CML), characterized by unregulated proliferation of
myeloid cells in the bone marrow, accounts for 15 to 20% of all adult leukemia cases in the …