Traumatic brain injury: neuropathological, neurocognitive and neurobehavioral sequelae
Traumatic brain injury (TBI) causes substantial neurological disabilities and mental distress.
Annual TBI incidence is in magnitude of millions, making it a global health challenge …
Annual TBI incidence is in magnitude of millions, making it a global health challenge …
Traumatic brain injury: a potential cause of violent crime?
WH Williams, P Chitsabesan, S Fazel… - The Lancet …, 2018 - thelancet.com
Traumatic brain injury (TBI) is the biggest cause of death and disability in children and
young people. TBI compromises important neurological functions for self-regulation and …
young people. TBI compromises important neurological functions for self-regulation and …
Multiangle, self-powered sensor array for monitoring head impacts
Mild concussions occur frequently and may come with long-term cognitive, affective, and
physical sequelae. However, the diagnosis of mild concussions lacks objective assessment …
physical sequelae. However, the diagnosis of mild concussions lacks objective assessment …
Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury
Axonal injury is a key determinant of long-term outcomes after traumatic brain injury (TBI) but
has been difficult to measure clinically. Fluid biomarker assays can now sensitively quantify …
has been difficult to measure clinically. Fluid biomarker assays can now sensitively quantify …
Effect of early sustained prophylactic hypothermia on neurologic outcomes among patients with severe traumatic brain injury: the POLAR randomized clinical trial
Importance After severe traumatic brain injury, induction of prophylactic hypothermia has
been suggested to be neuroprotective and improve long-term neurologic outcomes …
been suggested to be neuroprotective and improve long-term neurologic outcomes …
Risk of posttraumatic stress disorder and major depression in civilian patients after mild traumatic brain injury: a TRACK-TBI study
Importance Traumatic brain injury (TBI) has been associated with adverse mental health
outcomes, such as posttraumatic stress disorder (PTSD) and major depressive disorder …
outcomes, such as posttraumatic stress disorder (PTSD) and major depressive disorder …
Effect of continuous infusion of hypertonic saline vs standard care on 6-month neurological outcomes in patients with traumatic brain injury: the COBI randomized …
Importance Fluid therapy is an important component of care for patients with traumatic brain
injury, but whether it modulates clinical outcomes remains unclear. Objective To determine …
injury, but whether it modulates clinical outcomes remains unclear. Objective To determine …
Pathological computed tomography features associated with adverse outcomes after mild traumatic brain injury: a TRACK-TBI study with external validation in …
Importance A head computed tomography (CT) with positive results for acute intracranial
hemorrhage is the gold-standard diagnostic biomarker for acute traumatic brain injury (TBI) …
hemorrhage is the gold-standard diagnostic biomarker for acute traumatic brain injury (TBI) …
In Situ implantable, post-trauma microenvironment-responsive, ROS Depletion Hydrogels for the treatment of Traumatic brain injury
F Qian, Y Han, Z Han, D Zhang, L Zhang, G Zhao, S Li… - Biomaterials, 2021 - Elsevier
Traumatic brain injury (TBI) generates excess reactive oxygen species (ROS), which can
exacerbate secondary injury and result in disability and death. Secondary injury cascades …
exacerbate secondary injury and result in disability and death. Secondary injury cascades …
[HTML][HTML] Astrocyte-derived exosomes protect hippocampal neurons after traumatic brain injury by suppressing mitochondrial oxidative stress and apoptosis
W Zhang, J Hong, H Zhang, W Zheng, Y Yang - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
In this study, we investigated the mechanisms through which astrocyte-derived exosomes
(AS-Exos) alleviate traumatic brain injury (TBI)-induced neuronal defects in TBI model rats …
(AS-Exos) alleviate traumatic brain injury (TBI)-induced neuronal defects in TBI model rats …