recount3: summaries and queries for large-scale RNA-seq expression and splicing
We present recount3, a resource consisting of over 750,000 publicly available human and
mouse RNA sequencing (RNA-seq) samples uniformly processed by our new Monorail …
mouse RNA sequencing (RNA-seq) samples uniformly processed by our new Monorail …
Functional annotation of human long noncoding RNAs via molecular phenotyping
Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian
genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project …
genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project …
Molecular insight into the therapeutic potential of long non-coding RNA-associated competing endogenous RNA axes in alzheimer's disease: a systematic scoping …
Alzheimer's disease (AD) is a heterogeneous degenerative brain disorder with a rising
prevalence worldwide. The two hallmarks that characterize the AD pathophysiology are …
prevalence worldwide. The two hallmarks that characterize the AD pathophysiology are …
LncRNAs and available databases
S Napoli - Long Non-Coding RNAs in Cancer, 2021 - Springer
Long noncoding RNAs (lncRNAs) are involved in many regulatory mechanisms in practically
every step of the RNA cycle, from transcription to RNA stability and translation. They are a …
every step of the RNA cycle, from transcription to RNA stability and translation. They are a …
Pan-cancer genomic analysis shows hemizygous PTEN loss tumors are associated with immune evasion and poor outcome
In tumors, somatic mutations of the PTEN suppressor gene are associated with advanced
disease, chemotherapy resistance, and poor survival. PTEN loss of function may occur by …
disease, chemotherapy resistance, and poor survival. PTEN loss of function may occur by …
The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1
EK Gustavsson, S Sethi, Y Gao, JW Brenton… - Science …, 2024 - science.org
Mutations in GBA1 cause Gaucher disease and are the most important genetic risk factor for
Parkinson's disease. However, analysis of transcription at this locus is complicated by its …
Parkinson's disease. However, analysis of transcription at this locus is complicated by its …
Global Analysis of Transcription Start Sites in the New Ovine Reference Genome (Oar rambouillet v1.0)
The overall aim of the Ovine FAANG project is to provide a comprehensive annotation of the
new highly contiguous sheep reference genome sequence (Oar rambouillet v1. 0). Mapping …
new highly contiguous sheep reference genome sequence (Oar rambouillet v1. 0). Mapping …
Identification of androgen response‐related lncRNAs in prostate cancer
SK Karthikeyan, N Xu, JE Ferguson 3rd… - The …, 2023 - Wiley Online Library
Abstract Background Long noncoding RNAs (lncRNAs) are RNA molecules with over 200
nucleotides that do not code for proteins, but are known to be widely expressed and have …
nucleotides that do not code for proteins, but are known to be widely expressed and have …
Transcriptional landscape of PTEN loss in primary prostate cancer
Background PTEN is the most frequently lost tumor suppressor in primary prostate cancer
(PCa) and its loss is associated with aggressive disease. However, the transcriptional …
(PCa) and its loss is associated with aggressive disease. However, the transcriptional …
Epigenetic transcripts of LINC01311 and hsa‐miR‐146a‐5p regulate neural development in a cellular model of Alzheimer's disease
Y Fan, J Zhang, X Zhuang, F Geng, G Jiang… - IUBMB life, 2021 - Wiley Online Library
Emerging evidence has shown that Long noncoding RNAs (LncRNAs) are aberrantly
expressed and functionally involved in the development of neurodegenerative disorders. In …
expressed and functionally involved in the development of neurodegenerative disorders. In …