Prediabetes is an intermediate state of hyperglycemia with glycemic parameters above
normal but below the diabetes threshold. While, the diagnostic criteria of prediabetes are not …

Prediabetes (intermediate hyperglycaemia) is a high-risk state for diabetes that is defined by
glycaemic variables that are higher than normal, but lower than diabetes thresholds. 5–10 …

In the last two decades evidence has gradually accumulated suggesting that the eye may be
a unique window for cardiovascular risk stratification based on the assessment of subclinical …

We review the cellular and physiological mechanisms responsible for the regulation of blood
flow in the retina and choroid in health and disease. Due to the intrinsic light sensitivity of the …

Summary Prediabetes (or “intermediate hyperglycaemia”), based on glycaemic parameters
above normal but below diabetes thresholds is a high risk state for diabetes with an …

Endothelial dysfunction comprises a number of functional alterations in the vascular
endothelium that are associated with diabetes and cardiovascular disease, including …

Hypertension and diabetes share common risk factors and frequently co-occur. Although
high blood pressure (BP) was reported as a significant predictor of type 2 diabetes, little is …

Objective: Microvascular dysfunction has been suggested to be a major pathogenic factor for
the development of hypertension. We examined the association between retinal vascular …

Please cite this paper as: de Boer, Meijer, Wijnstok, Jonk, Houben, Stehouwer, Smulders,
Eringa and Serné (2012). Microvascular Dysfunction: A Potential Mechanism in the …

Essentially all biological processes fluctuate over the course of the day, observed at cellular
(eg, transcription, translation, and signaling), organ (eg, contractility and metabolism), and …