Seaweed protein hydrolysates and bioactive peptides: Extraction, purification, and applications
Seaweeds are industrially exploited for obtaining pigments, polysaccharides, or phenolic
compounds with application in diverse fields. Nevertheless, their rich composition in fiber …
compounds with application in diverse fields. Nevertheless, their rich composition in fiber …
Recent applications of light scattering measurement in the biological and biopharmaceutical sciences
AP Minton - Analytical biochemistry, 2016 - Elsevier
Measurement of the average intensity of excess scattering, termed static light scattering
(SLS), has become one of the most widely used techniques for the determination of molar …
(SLS), has become one of the most widely used techniques for the determination of molar …
IgG charge: practical and biological implications
D Yang, R Kroe-Barrett, S Singh, T Laue - Antibodies, 2019 - mdpi.com
Practically, IgG charge can contribute significantly to thermodynamic nonideality, and hence
to solubility and viscosity. Biologically, IgG charge isomers exhibit differences in clearance …
to solubility and viscosity. Biologically, IgG charge isomers exhibit differences in clearance …
Comparison of emulsifying properties of plant and animal proteins in oil-in-water emulsions: whey, soy, and RuBisCo proteins
There is increasing interest within the food industry in replacing animal-derived ingredients
with plant-derived alternatives. In this study, we compared the emulsifying properties of an …
with plant-derived alternatives. In this study, we compared the emulsifying properties of an …
Ribosome surface properties may impose limits on the nature of the cytoplasmic proteome
PE Schavemaker, WM Śmigiel, B Poolman - Elife, 2017 - elifesciences.org
Much of the molecular motion in the cytoplasm is diffusive, which possibly limits the tempo of
processes. We studied the dependence of protein mobility on protein surface properties and …
processes. We studied the dependence of protein mobility on protein surface properties and …
Optothermophoretic flipping method for biomolecule interaction enhancement
The widely used surface-based biomolecule sensing scheme has greatly facilitated the
investigation of protein-protein interactions in lab-on-a-chip microfluidic systems. However …
investigation of protein-protein interactions in lab-on-a-chip microfluidic systems. However …
Application of interpretable artificial neural networks to early monoclonal antibodies development
L Gentiluomo, D Roessner, D Augustijn… - European Journal of …, 2019 - Elsevier
The development of a new protein drug typically starts with the design, expression and
biophysical characterization of many different protein constructs. The initially high number of …
biophysical characterization of many different protein constructs. The initially high number of …
Advancing therapeutic protein discovery and development through comprehensive computational and biophysical characterization
L Gentiluomo, HL Svilenov, D Augustijn… - Molecular …, 2019 - ACS Publications
Therapeutic protein candidates should exhibit favorable properties that render them suitable
to become drugs. Nevertheless, there are no well-established guidelines for the efficient …
to become drugs. Nevertheless, there are no well-established guidelines for the efficient …
Challenges in predicting protein-protein interactions from measurements of molecular diffusivity
LL Sorret, MA DeWinter, DK Schwartz, TW Randolph - Biophysical journal, 2016 - cell.com
Dynamic light scattering can be used to measure the diffusivity of a protein within a
formulation. The dependence of molecular diffusivity on protein concentration (traditionally …
formulation. The dependence of molecular diffusivity on protein concentration (traditionally …
Optimizing the bioavailability of subcutaneously administered biotherapeutics through mechanochemical drivers
DS Collins, LC Kourtis, NR Thyagarajapuram… - Pharmaceutical …, 2017 - Springer
The subcutaneous route offers myriad benefits for the administration of biotherapeutics in
both acute and chronic diseases, including convenience, cost effectiveness and the …
both acute and chronic diseases, including convenience, cost effectiveness and the …