The fascination and fear of snakes dates back to time immemorial, with the first scientific
treatise on snakebite envenoming, the Brooklyn Medical Papyrus, dating from ancient Egypt …

1.1. Discovery of the Phospholipase A2 Superfamily Phospholipases represent one of the
earliest enzyme activities to be identified and studied, and the phospholipase A2 (PLA2) …

The phospholipase A2 (PLA2) superfamily of phospholipase enzymes hydrolyzes the ester
bond at the sn-2 position of the phospholipids, generating a free fatty acid and a …

Tremendous advances in understanding the structure and function of the superfamily of
phospholipase A 2 (PLA 2) enzymes has occurred in the twenty-first century. The …

The polyunsaturated fatty acids linoleate and alpha-linolenate are important membrane
components and are the essential fatty acids of human nutrition. The major enzyme …

LIPASES are hydrolytic enzymes which break down triacylglycerides into free fatty acids and
glycerols. They have been classified as serine hydrolases owing to their inhibition by diethyl …

The phospholipase A2 (PLA2) superfamily consists of a broad range of enzymes defined by
their ability to catalyze the hydrolysis of the middle (sn-2) ester bond of substrate …

Treatment of cells with agents that stimulate the release of arachldonic acid causes
increased serine phosphorylation and activation of cytosolic phospholipase A2 (cPLA*) …

From reviews to the first edtion:" Bornscheuer and Kazlauskas have set out, and succeeded,
in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and …

Acid-sensing ion channels (ASICs) detect extracellular protons produced during
inflammation or ischemic injury and belong to the superfamily of degenerin/epithelial sodium …