Cryogenic transmission electron microscopy (cryo-TEM) for studying the morphology of colloidal drug delivery systems

J Kuntsche, JC Horst, H Bunjes - International journal of pharmaceutics, 2011 - Elsevier
Cryogenic transmission electron microscopy (cryo-TEM) has evolved into an indispensable
tool for the characterization of colloidal drug delivery systems. It can be applied to study the …

Advances in drug delivery and medical imaging using colloidal lyotropic liquid crystalline dispersions

X Mulet, BJ Boyd, CJ Drummond - Journal of colloid and interface science, 2013 - Elsevier
The overarching goal of this feature article is to review the recent developments in the field
of drug delivery specifically involving colloidal lyotropic liquid crystalline dispersions. The …

Liquid crystalline inverted lipid phases encapsulating siRNA enhance lipid nanoparticle mediated transfection

R Pattipeiluhu, Y Zeng, MMRM Hendrix… - Nature …, 2024 - nature.com
Efficient cytosolic delivery of RNA molecules remains a formidable barrier for RNA
therapeutic strategies. Lipid nanoparticles (LNPs) serve as state-of-the-art carriers that can …

Lyotropic liquid crystal engineering moving beyond binary compositional space–ordered nanostructured amphiphile self-assembly materials by design

L van't Hag, SL Gras, CE Conn… - Chemical society …, 2017 - pubs.rsc.org
Ordered amphiphile self-assembly materials with a tunable three-dimensional (3D)
nanostructure are of fundamental interest, and crucial for progressing several biological and …

Advances in lyotropic liquid crystal systems for skin drug delivery

AVP Silvestrini, AL Caron, J Viegas… - Expert Opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction Lyotropic liquid crystals (LLCs) are organized mesophases with
intermediate properties between liquids and solids. The LLC and its liquid crystalline …

Cubosomes and hexosomes as novel nanocarriers for bioactive compounds

C Tan, SF Hosseini, SM Jafari - Journal of Agricultural and Food …, 2022 - ACS Publications
Cubosomes and hexosomes are nanostructured liquid crystalline particles, known as
biocompatible nanocarriers for drug delivery. In recent years, there has been good interest …

Advances in lipid and metal nanoparticles for antimicrobial peptide delivery

M Makowski, ÍC Silva, C Pais do Amaral, S Gonçalves… - Pharmaceutics, 2019 - mdpi.com
Antimicrobial peptides (AMPs) have been described as excellent candidates to overcome
antibiotic resistance. Frequently, AMPs exhibit a wide therapeutic window, with low …

Cubosomes and hexosomes as versatile platforms for drug delivery

IDM Azmi, SM Moghimi, A Yaghmur - Therapeutic delivery, 2015 - Taylor & Francis
Nonlamellar liquid crystalline phases are attractive platforms for drug solubilization and
targeted delivery. The attractiveness of this formulation principle is linked to the …

Recent advances in nanomaterials for dermal and transdermal applications

A Zoabi, E Touitou, K Margulis - Colloids and Interfaces, 2021 - mdpi.com
The stratum corneum, the most superficial layer of the skin, protects the body against
environmental hazards and presents a highly selective barrier for the passage of drugs and …

Liquid crystalline nanoparticles enable a multifunctional approach for topical psoriasis therapy by co-delivering triptolide and siRNAs

AVP Silvestrini, FG Praça, MN Leite… - International Journal of …, 2023 - Elsevier
Liquid crystalline nanoparticles (LCNs) are an attractive drugs topical delivery system due to
the great internal ordering, wide interfacial area and structural similarities with the skin. In …