Diffuse large B‐cell lymphoma: 2019 update on diagnosis, risk stratification, and treatment

Y Liu, SK Barta - American journal of hematology, 2019 - Wiley Online Library
Abstract Disease Overview Diffuse large B‐cell lymphoma (DLBCL) is the most common
type of aggressive non‐Hodgkin lymphoma originating from the germinal center, and it …

Refinement of the Lugano Classification lymphoma response criteria in the era of immunomodulatory therapy

BD Cheson, S Ansell, L Schwartz… - Blood, The Journal …, 2016 - ashpublications.org
Uniformly adopted response criteria are essential for assessment of therapies incorporating
conventional chemotherapy and chemoimmunotherapy regimens. Recently …

Tafasitamab plus lenalidomide in relapsed or refractory diffuse large B-cell lymphoma (L-MIND): a multicentre, prospective, single-arm, phase 2 study

G Salles, J Duell, EG Barca, O Tournilhac… - The Lancet …, 2020 - thelancet.com
Background Patients with relapsed or refractory diffuse large B-cell lymphoma who are
ineligible for autologous stem-cell transplantation have poor outcomes and few treatment …

ROBUST: a phase III study of lenalidomide plus R-CHOP versus placebo plus R-CHOP in previously untreated patients with ABC-type diffuse large B-cell lymphoma

GS Nowakowski, A Chiappella… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE Patients with the activated B-cell-like (ABC) subtype of diffuse large B-cell
lymphoma (DLBCL) historically showed inferior survival with standard rituximab plus …

[HTML][HTML] Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell …

J Duell, KJ Maddocks, E González-Barca… - …, 2021 - ncbi.nlm.nih.gov
Abstract Tafasitamab (MOR208), an Fc-modified, humanized, anti-CD19 monoclonal
antibody, combined with the immunomodulatory drug lenalidomide was clinically active with …

Combination Targeted Therapy in Relapsed Diffuse Large B-Cell Lymphoma

C Melani, R Lakhotia, S Pittaluga… - … England Journal of …, 2024 - Mass Medical Soc
Background The identification of oncogenic mutations in diffuse large B-cell lymphoma
(DLBCL) has led to the development of drugs that target essential survival pathways, but …

Diffuse large B-cell lymphoma: optimizing outcome in the context of clinical and biologic heterogeneity

LH Sehn, RD Gascoyne - Blood, The Journal of the American …, 2015 - ashpublications.org
Although the majority of patients with diffuse large B-cell lymphoma (DLBCL) can be cured
with standard rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R …

The tumour microenvironment in B cell lymphomas

DW Scott, RD Gascoyne - Nature Reviews Cancer, 2014 - nature.com
B cell lymphomas are cancers that arise from cells that depend on numerous highly
orchestrated interactions with immune and stromal cells in the course of normal …

Phase 2 study of the bispecific T-cell engager (BiTE) antibody blinatumomab in relapsed/refractory diffuse large B-cell lymphoma

A Viardot, ME Goebeler, G Hess… - Blood, The Journal …, 2016 - ashpublications.org
Few patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL) achieve
prolonged disease-free survival. Blinatumomab, a bispecific T-cell engaging antibody …

Lenalidomide combined with R-CHOP overcomes negative prognostic impact of non–germinal center B-cell phenotype in newly diagnosed diffuse large B-cell …

GS Nowakowski, B LaPlant, WR Macon… - Journal of clinical …, 2015 - ascopubs.org
Purpose Lenalidomide has significant single-agent activity in relapsed diffuse large B-cell
lymphoma (DLBCL). We demonstrated that lenalidomide can be safely combined with R …