The statistical analysis of crash-frequency data: A review and assessment of methodological alternatives

D Lord, F Mannering - Transportation research part A: policy and practice, 2010 - Elsevier
Gaining a better understanding of the factors that affect the likelihood of a vehicle crash has
been an area of research focus for many decades. However, in the absence of detailed …

Nirmatrelvir plus ritonavir for early COVID-19 in a large US health system: a population-based cohort study

S Dryden-Peterson, A Kim, AY Kim… - Annals of internal …, 2023 - acpjournals.org
Background: In the EPIC-HR (Evaluation of Protease Inhibition for Covid-19 in High-Risk
Patients) trial, nirmatrelvir plus ritonavir led to an 89% reduction in hospitalization or death …

Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)

JJA van Kampen, DAMC van de Vijver… - Nature …, 2021 - nature.com
Key questions in COVID-19 are the duration and determinants of infectious virus shedding.
Here, we report that infectious virus shedding is detected by virus cultures in 23 of the 129 …

Evolutionary forces favoring intragroup coalitions among spotted hyenas and other animals

JE Smith, RC Van Horn, KS Powning… - Behavioral …, 2010 - academic.oup.com
Coalitionary support in agonistic interactions represents cooperation because intervening in
a fight is potentially costly to the donor of support but benefits the recipient. Here, we first …

SARS-CoV-2 viral clearance and evolution varies by type and severity of immunodeficiency

Y Li, MC Choudhary, J Regan, J Boucau… - Science translational …, 2024 - science.org
Despite vaccination and antiviral therapies, immunocompromised individuals are at risk for
prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but the …

Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants

J Samara, S Moossavi, B Alshaikh, VA Ortega… - Cell host & …, 2022 - cell.com
Probiotics are increasingly administered to premature infants to prevent necrotizing
enterocolitis and neonatal sepsis. However, their effects on gut microbiome assembly and …

Precision microbiome modulation with discrete dietary fiber structures directs short-chain fatty acid production

EC Deehan, C Yang, ME Perez-Muñoz, NK Nguyen… - Cell host & …, 2020 - cell.com
Dietary fibers (DFs) impact the gut microbiome in ways often considered beneficial.
However, it is unknown if precise and predictable manipulations of the gut microbiota, and …

The infant gut virome is associated with preschool asthma risk independently of bacteria

C Leal Rodríguez, SA Shah, MA Rasmussen… - Nature Medicine, 2024 - nature.com
Bacteriophage (also known as phage) communities that inhabit the gut have a major effect
on the structure and functioning of bacterial populations, but their roles and association with …

Zika virus infection enhances future risk of severe dengue disease

LC Katzelnick, C Narvaez, S Arguello… - Science, 2020 - science.org
The Zika pandemic sparked intense interest in whether immune interactions among dengue
virus serotypes 1 to 4 (DENV1 to-4) extend to the closely related Zika virus (ZIKV). We …

Are gender gaps due to evaluations of the applicant or the science? A natural experiment at a national funding agency

HO Witteman, M Hendricks, S Straus, C Tannenbaum - The Lancet, 2019 - thelancet.com
Background Across countries and disciplines, studies show male researchers receive more
research funding than their female peers. Because most studies have been observational, it …