Abstract 'Autophagy'refers to an evolutionarily conserved process through which cellular
contents, such as damaged organelles and protein aggregates, are delivered to lysosomes …

The Wnt pathway is central to a host of developmental and disease-related processes. The
remarkable conservation of this intercellular signaling cascade throughout metazoan …

The application of metal–organic frameworks (MOFs) in drug delivery has advanced rapidly
over the past decade, showing huge progress in the development of novel systems …

An abundant supply of amino acids is important for cancers to sustain their proliferative
drive. Alongside their direct role as substrates for protein synthesis, they can have roles in …

Wnt signaling has multiple functions beyond the transcriptional effects of β-catenin
stabilization. We review recent investigations that uncover new cell physiological effects …

Beginning with the earliest studies of autophagy in cancer, there have been indications that
autophagy can both promote and inhibit cancer growth and progression; autophagy …

Macropinocytosis is defined as an actin-dependent but coat-and dynamin-independent
endocytic uptake process, which generates large intracellular vesicles (macropinosomes) …

Eukaryotic cells engage in autophagy, an internal process of self-degradation through
lysosomes. Autophagy can be classified as selective or non-selective depending on the way …

The mammalian target of rapamycin complex1 (mTORC1) is a central regulator of
metabolism and cell growth by sensing diverse environmental signals, including amino …

Wnt/β‐catenin signaling is an ancient pathway that regulates key aspects of embryonic
development, cell differentiation, proliferation, and adult stem cell homeostasis. Work from …