[HTML][HTML] Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

[HTML][HTML] Integrative neuroinformatics for precision prognostication and personalized therapeutics in moderate and severe traumatic brain injury

FA Zeiler, Y Iturria-Medina, EP Thelin, A Gomez… - Frontiers in …, 2021 - frontiersin.org
Despite changes in guideline-based management of moderate/severe traumatic brain injury
(TBI) over the preceding decades, little impact on mortality and morbidity have been seen …

Post-acute blood biomarkers and disease progression in traumatic brain injury

VFJ Newcombe, NJ Ashton, JP Posti, B Glocker… - Brain, 2022 - academic.oup.com
There is substantial interest in the potential for traumatic brain injury to result in progressive
neurological deterioration. While blood biomarkers such as glial fibrillary acid protein …

Prognostic models for global functional outcome and post-concussion symptoms following mild traumatic brain injury: a Collaborative European NeuroTrauma …

A Mikolić, EW Steyerberg, S Polinder… - Journal of …, 2023 - liebertpub.com
After mild traumatic brain injury (mTBI), a substantial proportion of individuals do not fully
recover on the Glasgow Outcome Scale Extended (GOSE) or experience persistent post …

PREdiction and Diagnosis using Imaging and Clinical biomarkers Trial in Traumatic Brain Injury (PREDICT-TBI) study protocol: an observational, prospective …

F Nasrallah, J Bellapart, J Walsham, E Jacobson… - BMJ open, 2023 - bmjopen.bmj.com
Introduction Traumatic brain injury (TBI) is a heterogeneous condition with a broad spectrum
of injury severity, pathophysiological processes and variable outcomes. For moderate-to …

Use of support vector machines approach via combat harmonized diffusion tensor imaging for the diagnosis and prognosis of mild traumatic brain injury: a CENTER …

M Siqueira Pinto, S Winzeck… - Journal of …, 2023 - liebertpub.com
The prediction of functional outcome after mild traumatic brain injury (mTBI) is challenging.
Conventional magnetic resonance imaging (MRI) does not do a good job of explaining the …

Trajectories of brain volumes in young children are associated with maternal education

C Zhu, Y Chen, HG Müller, JL Wang… - Human brain …, 2023 - Wiley Online Library
Brain growth in early childhood is reflected in the evolution of proportional cerebrospinal
fluid volumes (pCSF), grey matter (pGM), and white matter (pWM). We study brain …

[HTML][HTML] Serum biomarkers identify critically ill traumatic brain injury patients for MRI

S Richter, S Winzeck, E Czeiter, K Amrein… - Critical Care, 2022 - Springer
Background Magnetic resonance imaging (MRI) carries prognostic importance after
traumatic brain injury (TBI), especially when computed tomography (CT) fails to fully explain …

Fluid biomarkers and neuroimaging in mild traumatic brain injury: current uses and potential future directions for clinical use in emergency medicine

V Newcombe, S Richter, DP Whitehouse… - Emergency medicine …, 2023 - emj.bmj.com
Mild traumatic brain injury is a common presentation to the emergency department, with
current management often focusing on determining whether a patient requires a CT head …

The prognostic role of magnetic resonance imaging biomarkers in mild traumatic injury

E Massaad, JH Shin, WN Gibbs - JAMA network open, 2021 - jamanetwork.com
Traumatic brain injury (TBI) is a serious public health concern and the reason for nearly 2.8
million of the 26 million injury-related emergency department visits, hospitalizations, and …