Engineered living materials: prospects and challenges for using biological systems to direct the assembly of smart materials
PQ Nguyen, NMD Courchesne… - Advanced …, 2018 - Wiley Online Library
Vast potential exists for the development of novel, engineered platforms that manipulate
biology for the production of programmed advanced materials. Such systems would possess …
biology for the production of programmed advanced materials. Such systems would possess …
Designing cell function: assembly of synthetic gene circuits for cell biology applications
M Xie, M Fussenegger - Nature Reviews Molecular Cell Biology, 2018 - nature.com
Synthetic biology is the discipline of engineering application-driven biological functionalities
that were not evolved by nature. Early breakthroughs of cell engineering, which were based …
that were not evolved by nature. Early breakthroughs of cell engineering, which were based …
Programming self-organizing multicellular structures with synthetic cell-cell signaling
A common theme in the self-organization of multicellular tissues is the use of cell-cell
signaling networks to induce morphological changes. We used the modular synNotch …
signaling networks to induce morphological changes. We used the modular synNotch …
Biological engineered living materials: growing functional materials with genetically programmable properties
C Gilbert, T Ellis - ACS synthetic biology, 2018 - ACS Publications
Natural biological materials exhibit remarkable properties: self-assembly from simple raw
materials, precise control of morphology, diverse physical and chemical properties, self …
materials, precise control of morphology, diverse physical and chemical properties, self …
[HTML][HTML] Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis
E Izquierdo, T Quinkler, S De Renzis - Nature communications, 2018 - nature.com
During organismal development, cells undergo complex changes in shape whose causal
relationship to individual morphogenetic processes remains unclear. The modular nature of …
relationship to individual morphogenetic processes remains unclear. The modular nature of …
[HTML][HTML] A synthetic bacterial cell-cell adhesion toolbox for programming multicellular morphologies and patterns
DS Glass, IH Riedel-Kruse - Cell, 2018 - cell.com
Synthetic multicellular systems hold promise as models for understanding natural
development of biofilms and higher organisms and as tools for engineering complex multi …
development of biofilms and higher organisms and as tools for engineering complex multi …
Hybrid living materials: digital design and fabrication of 3D multimaterial structures with programmable biohybrid surfaces
Significant efforts exist to develop living/non‐living composite materials—known as
biohybrids—that can support and control the functionality of biological agents. To enable the …
biohybrids—that can support and control the functionality of biological agents. To enable the …
[HTML][HTML] Context-aware synthetic biology by controller design: Engineering the mammalian cell
The rise of systems biology has ushered a new paradigm: the view of the cell as a system
that processes environmental inputs to drive phenotypic outputs. Synthetic biology provides …
that processes environmental inputs to drive phenotypic outputs. Synthetic biology provides …
Cell competition during reprogramming gives rise to dominant clones
INTRODUCTION Recent advances in lineage tracking using DNA-based barcoding
technologies have provided new insights into the developmental dynamics of cell …
technologies have provided new insights into the developmental dynamics of cell …
[HTML][HTML] Liquid crystal elastomers for biological applications
The term liquid crystal elastomer (LCE) describes a class of materials that combine the
elastic entropy behaviour associated with conventional elastomers with the stimuli …
elastic entropy behaviour associated with conventional elastomers with the stimuli …