Abstract Purpose of Review This review summarizes studies highlighting perfluoroalkyl
substances (PFAS) and their effects on the placenta, pregnancy outcomes, and child health …

The root cause of preeclampsia is the placenta. Preeclampsia begins to abate with the
delivery of the placenta and can occur in the absence of a fetus but with the presence of …

Preeclampsia is a disease of the mother, fetus, and placenta, and the gaps in our
understanding of the complex interactions among their respective disease pathways …

Background: Patients with preeclampsia display a spectrum of onset time and severity of
clinical presentation, yet the underlying molecular bases for the early-onset and late-onset …

BACKGROUND The placenta is the active interface between mother and foetus, bearing the
molecular marks of rapid development and exposures in utero. The placenta is routinely …

As the primary interface between maternal and fetal circulations, the placenta is subject to a
myriad of environmental exposures with the capacity to alter placental function and fetal …

Background Preeclampsia (PE) is a heterogeneous, hypertensive disorder of pregnancy,
with no robust biomarkers or effective treatments. We hypothesized that this heterogeneity is …

Tumor progression and pregnancy share many common features, such as immune
tolerance and invasion. The invasion of trophoblasts in the placenta into the uterine wall is …

Background A small number of recent reports have suggested that altered placental DNA
methylation may be associated with early onset preeclampsia. It is important that further …

Objective To systematically review the literature on human gene expression data of
placental tissue in pre-eclampsia and to characterize a meta-signature of differentially …