Incorporating ecology into gene drive modelling

J Kim, KD Harris, IK Kim, S Shemesh… - Ecology …, 2023 - Wiley Online Library
Gene drive technology, in which fast‐spreading engineered drive alleles are introduced into
wild populations, represents a promising new tool in the fight against vector‐borne diseases …

[HTML][HTML] MGSurvE: A framework to optimize trap placement for genetic surveillance of mosquito populations

DL Smith, JM Marshall - PLOS Computational Biology, 2024 - ncbi.nlm.nih.gov
Genetic surveillance of mosquito populations is becoming increasingly relevant as genetics-
based mosquito control strategies advance from laboratory to field testing. Especially …

MGSurvE: A framework to optimize trap placement for genetic surveillance of mosquito population

HM Sánchez C, DL Smith, JM Marshall - bioRxiv, 2023 - biorxiv.org
Genetic surveillance of mosquito populations is becoming increasingly relevant as genetics-
based mosquito control strategies advance from laboratory to field testing. Especially …

Measuring the Impact of Genetic Heterogeneity and Chromosomal Inversions on the Efficacy of CRISPR-Cas9 Gene Drives in Different Strains of Anopheles gambiae

P Pescod, G Bevivino, A Anthousi, R Shelton… - The CRISPR …, 2023 - liebertpub.com
The human malaria vector Anopheles gambiae is becoming increasingly resistant to
insecticides, spurring the development of genetic control strategies. CRISPR-Cas9 gene …

MGSurvE: A framework to optimize trap placement for genetic surveillance of mosquito populations

HM Sánchez C, DL Smith… - PLoS Computational …, 2024 - journals.plos.org
Genetic surveillance of mosquito populations is becoming increasingly relevant as genetics-
based mosquito control strategies advance from laboratory to field testing. Especially …

Gene drives for the extinction of wild metapopulations

JW Olejarz, MA Nowak - Journal of Theoretical Biology, 2024 - Elsevier
Population-suppressing gene drives may be capable of extinguishing wild populations, with
proposed applications in conservation, agriculture, and public health. However, unintended …

Stochastic extinction of epidemics: How long would it take for SARS-CoV-2 to die out without herd immunity?

BS Khatri - medRxiv, 2020 - medrxiv.org
Worldwide, we are currently in an unprecedented situation with regard to the SARS-Cov-2
epidemic, where countries are using isolation and lock-down measures to control the spread …

[HTML][HTML] A simple stochastic theory of extinction shows rapid elimination of a Sars-like pandemic

BS Khatri - 2020 - europepmc.org
The SARS-Cov-2 pandemic has seen the challenge of controlling novel zoonotic diseases
that have high infection fatality rates, including a natural capacity for the evolution of variants …