Long non-coding RNA in stem cell pluripotency and lineage commitment: functions and evolutionary conservation

A Fico, A Fiorenzano, E Pascale, EJ Patriarca… - Cellular and molecular …, 2019 - Springer
LncRNAs have recently emerged as new and fundamental transcriptional and post-
transcriptional regulators acting at multiple levels of gene expression. Indeed, lncRNAs …

Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system

J Zhou, R Wang, J Zhang, L Zhu, W Liu, S Lu… - … et Biophysica Acta (BBA …, 2017 - Elsevier
T-UCRs, a class of long non-coding RNAs that are transcribed from ultra-conserved regions
(UCRs), might play an important role in development and diseases. However, the amount of …

Long Non-coding RNA T-uc.189 Modulates Neural Progenitor Cell Fate by Regulating Srsf3 During Mouse Cerebral Cortex Development

M Zhang, J Zhou, L Jiao, L Xu, L Hou, B Yin… - Frontiers in …, 2021 - frontiersin.org
Neurogenesis is a complex process that depends on the delicate regulation of spatial and
temporal gene expression. In our previous study, we found that transcribed ultra-conserved …

Ischemic stroke alters the expression of the transcribed ultraconserved regions of the genome in rat brain

SL Mehta, R Vemuganti - Stroke, 2018 - Am Heart Assoc
Background and Purpose—Human and rodent genomes diverged≈ 75 million years ago.
However, 481 regions of their genomes (200–779 nucleotide each) remained absolutely …

El transcriptoma no codificante en Síndrome de Rett: nuevas funciones para las regiones transcritas ultraconservadas y circRNAs

A Obiols Guardia - 2020 - diposit.ub.edu
[eng] Diversos estudios transcripcionales actuales ponen de manifiesto la importancia
funcional de la porción no codificante de nuestro genoma, observándose un papel crucial …