DNA methylation is one of the most important epigenetic mechanisms to regulate gene
expression, which is highly dynamic during development and specifically maintained in …

Long non-coding ribonucleic acids (RNAs)(lncRNAs) are key players in tumorigenesis and
immune responses. The nature of their cell type-specific gene expression and other …

Background Ferroptosis is a newly defined form of regulated cell death characterized by the
iron-dependent accumulation of lipid peroxidation and is involved in various …

Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

Background Tamoxifen resistance remains a clinical challenge for hormone receptor-
positive breast cancer. Recently, dysregulations in autophagy have been suggested as a …

Methionine restriction (MetR) extends lifespan across different species and exerts beneficial
effects on metabolic health and inflammatory responses. In contrast, certain cancer cells …

Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …

Simple Summary This review discusses the role of non-coding RNAs (ncRNAs) in cancer
epigenetics, mostly focusing on how deregulated microRNAs (miRNAs) and long non …

The rapid development of new generation sequencing technology has deepened the
understanding of genomes and functional products. RNA-sequencing studies in mammals …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …