Mammalian carboxylesterases (CEs) are key enzymes from the serine hydrolase
superfamily. In the human body, two predominant carboxylesterases (CES1 and CES2) …

Mammalian carboxylesterases are key serine hydrolases that catalyze the hydrolysis of a
wide variety of ester compounds in the corresponding carboxylic acids and alcohols. In …

Herein, we report a novel fluorescent “light‐up” probe useful for carboxylesterase assay that
is based on a tetraphenylethylene derivative containing carboxylic ester groups. The specific …

Carboxylesterases (CESs) play major roles in catalyzing the hydrolysis of a wide range of
ester-and amide-containing compounds. CESs dominate both the biotransformation of …

Effective use of exogenous human BChE as a bioscavenger for organophosphorus toxicants
(OPs) is hindered by its limited availability and rapid clearance. Complexes made from …

Chrysin is a widely distributed natural flavonoid with broad biological activities, but its poor
bioavailability and insufficient efficacy limit its clinical applications. Based on prodrug and …

A series of phosphorylated flavonoids has been synthesized and evaluated in vitro for
inhibitory activity against carboxylesterase, acetylcholinesterase and butyrylcholinesterase …

Organophosphate inhibits carboxylesterase thus regular treatment includes
carboxylesterase oxime reactivator in combination with anti-muscarinic agents. In order to …

Mammalian carboxylesterases are key serine hydrolases that catalyze the hydrolysis of a
wide variety of ester compounds in the corresponding carboxylic acids and alcohols. In …

Pharmaceutical Biocatalysis Page 1 Grunw ald Pharmaceutical Biocatalysis Pharmaceutical
Biocatalysis Fundamentals, Enzyme Inhibitors, and Enzymes in Health and Diseases Peter …