Cold Kit Labeling: The Future of 68Ga Radiopharmaceuticals?

N Lepareur - Frontiers in Medicine, 2022 - frontiersin.org
Over the last couple of decades, gallium-68 (68Ga) has gained a formidable interest for PET
molecular imaging of various conditions, from cancer to infection, through cardiac …

Copper, gallium and zirconium positron emission tomography imaging agents: The importance of metal ion speciation

LE McInnes, SE Rudd, PS Donnelly - Coordination Chemistry Reviews, 2017 - Elsevier
Positron emission tomography (PET) is a medical diagnostic imaging technique that
requires administration of a β+-emitting radiotracer to a patient. Metal-based PET …

Continued rapid growth in 68Ga applications: update 2013 to June 2014

I Velikyan - Journal of Labelled Compounds and …, 2015 - Wiley Online Library
The worldwide utilization of 68Ga‐radionuclide for the fundamental research and clinical
applications is growing exponentially. A broad range of 68Ga‐based imaging agents has …

Radiolabeling Strategies of Micron- and Submicron-Sized Core–Shell Carriers for In Vivo Studies

MV Zyuzin, D Antuganov… - … applied materials & …, 2020 - ACS Publications
Core–shell particles made of calcium carbonate and coated with biocompatible polymers
using the Layer-by-Layer technique can be considered as a unique drug-delivery platform …

Hydrolytically Degradable Zwitterionic Polyphosphazene Containing HEPES Moieties as Side Groups

HD Tagad, A Marin, R Hlushko… - Biomacromolecules, 2024 - ACS Publications
Zwitterionic polymers, ampholytic macromolecules containing ionic moieties of opposite sign
on the same pendant groups, exhibit strong protein-repulsive properties and an inherent …

N-Benzylethanolammonium Ionic Liquids and Molten Salts in the Synthesis of 68Ga- and Al18F-Labeled Radiopharmaceuticals

YA Kondratenko, JS Shilova, VA Gavrilov, AA Zolotarev… - Pharmaceutics, 2023 - mdpi.com
Ionic liquids (ILs), due to their structural features, have unique physical and chemical
properties and are environmentally friendly. Every year, the number of studies devoted to the …

Diethanolammonium protic ionic liquids-promising buffers for the synthesis of 68Ga-labelled radiopharmaceuticals

YA Kondratenko, DO Antuganov, AA Zolotarev… - Journal of Molecular …, 2022 - Elsevier
Fifteen new protic ionic liquids based on diethanolammonium (DEA) salts of carboxylic acids
have been synthesized and identified using a complex of physicochemical methods (NMR …

Synthesis and evaluation of 68Ga‐HBED‐CC‐EDBE‐folate for positron‐emission tomography imaging of overexpressed folate receptors on CT26 tumor cells

PS Choi, JY Lee, JH Park… - Journal of Labelled …, 2018 - Wiley Online Library
The 68Ga is a positron‐emitting radionuclide that can be combined with bifunctional
chelating agents and bioactive substances for use as positron‐emission tomography (PET) …

Assay Development for Metal-Dependent Enzymes─ Influence of Reaction Buffers on Activities and Kinetic Characteristics

N Forero, C Liu, SG Sabbah, MC Loewen, TC Yang - ACS omega, 2023 - ACS Publications
Buffers are often thought of as innocuous components of a reaction, with the sole task of
maintaining the pH of a system. However, studies had shown that this is not always the case …

68Ga-labeled phage-display selected peptides as tracers for positron emission tomography imaging of Staphylococcus aureus biofilm-associated infections: Selection …

KM Nielsen, MH Kyneb, AKO Alstrup, JJ Jensen… - Nuclear Medicine and …, 2016 - Elsevier
Introduction Staphylococcus aureus is a major cause of skin and deep-sited infections, often
associated with the formation of biofilms. Early diagnosis and initiated therapy is essential to …