Coronaviruses are a large group of enveloped, single-stranded positive-sense RNA viruses
that infect a wide range of avian and mammalian species, including humans. The …

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract disease in
young children and elderly people. Although the virus was isolated in 1955, an effective …

Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly identified
betacoronavirus causing high morbidity and mortality in humans. The coronavirus spike (S) …

A wide variety of viruses exploit furin and other proprotein convertases (PCs) of the
constitutive protein secretion pathway in order to regulate their cell entry mechanism and …

The coronavirus spike protein (S) plays a key role in the early steps of viral infection, with the
S1 domain responsible for receptor binding and the S2 domain mediating membrane fusion …

Human respiratory syncytial virus (RSV) is an enveloped, nonsegmented negative-strand
RNA virus of family Paramyxoviridae. RSV is the most complex member of the family in …

The two major glycoproteins on the surface of the respiratory syncytial virus (RSV) virion, the
attachment glycoprotein (G) and the fusion glycoprotein (F), control the initial phases of …

Furin catalyses a simple biochemical reaction—the proteolytic maturation of proprotein
substrates in the secretory pathway. But the simplicity of this reaction belies furin's broad and …

Human respiratory syncytial virus (RSV) is a ubiquitous pathogen that infects everyone
worldwide early in life and is a leading cause of severe lower respiratory tract disease in the …

Respiratory Syncytial Virus (RSV) is a highly pathogenic member of the Paramyxoviridae
that causes severe respiratory tract infections. Reports in the literature have indicated that to …