Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the
extracellular environment are packaged, sorted and internalized into cells. Endocytosis is …

Cancer cells possess remarkable abilities to adapt to adverse environmental conditions.
Their survival during severe nutrient and oxidative stress depends on their capacity to …

Acidosis, a common characteristic of the tumor microenvironment, is associated with
alterations in metabolic preferences of cancer cells and progression of the disease. Here we …

While cancer is commonly described as “a disease of the genes,” it is also associated with
massive metabolic reprogramming that is now accepted as a disease “Hallmark.” This …

During the past decade, there has been a paradigm shift in our understanding of the roles of
intracellular lipid droplets (LDs). New genetic, biochemical and imaging technologies have …

The extracellular pH of solid tumors is unequivocally acidic due to a combination of high
rates of lactic acid production (a consequence of fermentative glycolytic metabolism) and …

Purpose To analyze baseline CT/MR-based image features of salivary glands to predict
radiation-induced xerostomia 3-months after head-and-neck cancer (HNC) radiotherapy …

Human cancers represent complex structures, which display substantial inter-and intratumor
heterogeneity in their genetic expression and phenotypic features. However, cancers …

Cells exposed to stress of different origins synthesize triacylglycerols and generate lipid
droplets (LD), but the physiological relevance of this response is uncertain. Using complete …