[HTML][HTML] Necroptosis, pyroptosis and apoptosis: an intricate game of cell death
Cell death is a fundamental physiological process in all living organisms. Its roles extend
from embryonic development, organ maintenance, and aging to the coordination of immune …
from embryonic development, organ maintenance, and aging to the coordination of immune …
Intrinsic and extrinsic pathways of apoptosis: Role in cancer development and prognosis
Apoptosis, also named programmed cell death, is a fundament process required for
morphogenetic homeostasis during early development and in pathophysiological …
morphogenetic homeostasis during early development and in pathophysiological …
A review on caspases: key regulators of biological activities and apoptosis
G Sahoo, D Samal, P Khandayataray… - Molecular neurobiology, 2023 - Springer
Caspases are proteolytic enzymes that belong to the cysteine protease family and play a
crucial role in homeostasis and programmed cell death. Caspases have been broadly …
crucial role in homeostasis and programmed cell death. Caspases have been broadly …
[HTML][HTML] Cyclin-dependent kinases (CDK) and their role in diseases development–review
P Łukasik, M Załuski, I Gutowska - International journal of molecular …, 2021 - mdpi.com
Cyclin-dependent kinases (CDKs) are involved in many crucial processes, such as cell cycle
and transcription, as well as communication, metabolism, and apoptosis. The kinases are …
and transcription, as well as communication, metabolism, and apoptosis. The kinases are …
[HTML][HTML] Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
L Galluzzi, I Vitale, JM Abrams, ES Alnemri… - Cell Death & …, 2012 - nature.com
Abstract In 2009, the Nomenclature Committee on Cell Death (NCCD) proposed a set of
recommendations for the definition of distinct cell death morphologies and for the …
recommendations for the definition of distinct cell death morphologies and for the …
Cellular mechanisms controlling caspase activation and function
AB Parrish, CD Freel… - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
Caspases are the primary drivers of apoptotic cell death, cleaving cellular proteins that are
critical for dismantling the dying cell. Initially translated as inactive zymogenic precursors …
critical for dismantling the dying cell. Initially translated as inactive zymogenic precursors …
[HTML][HTML] Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
O Micheau, J Tschopp - Cell, 2003 - cell.com
Apoptosis induced by TNF-receptor I (TNFR1) is thought to proceed via recruitment of the
adaptor FADD and caspase-8 to the receptor complex. TNFR1 signaling is also known to …
adaptor FADD and caspase-8 to the receptor complex. TNFR1 signaling is also known to …
[HTML][HTML] Anticancer applications and pharmacological properties of piperidine and piperine: a comprehensive review on molecular mechanisms and therapeutic …
S Mitra, U Anand, NK Jha, MS Shekhawat… - Frontiers in …, 2022 - frontiersin.org
Piperine and piperidine are the two major alkaloids extracted from black pepper (Piper
nigrum); piperidine is a heterocyclic moiety that has the molecular formula (CH2) 5NH. Over …
nigrum); piperidine is a heterocyclic moiety that has the molecular formula (CH2) 5NH. Over …
Caspase family proteases and apoptosis
TJ Fan, LH Han, RS Cong, J Liang - Acta biochimica et …, 2005 - academic.oup.com
Apoptosis, or programmed cell death, is an essential physiological process that plays a
critical role in development and tissue homeostasis. The progress of apoptosis is regulated …
critical role in development and tissue homeostasis. The progress of apoptosis is regulated …
Mechanisms of cell death in oxidative stress
SW Ryter, HP Kim, A Hoetzel, JW Park… - Antioxidants & redox …, 2007 - liebertpub.com
Reactive oxygen or nitrogen species (ROS/RNS) generated endogenously or in response to
environmental stress have long been implicated in tissue injury in the context of a variety of …
environmental stress have long been implicated in tissue injury in the context of a variety of …