Biopolymer nanofibrils exhibit exceptional mechanical properties with a unique combination
of strength and toughness, while also presenting biological functions that interact with the …

Bone is a natural composite material consisting of an organic phase (collagen) and a
mineral phase (calcium phosphate, especially hydroxyapatite). The strength of bone is …

We have explored the applicability of printed scaffold by comparing osteogenic ability and
biodegradation property of three resorbable biomaterials. A polylactic acid/hydroxyapatite …

The regeneration of artificial bone substitutes is a potential strategy for repairing bone
defects. However, the development of substitutes with appropriate osteoinductivity and …

Biomimetic designs based on micro/nanoscale manipulation and scalable fabrication are
expected to develop new-style strong, tough structural materials. Although the mimicking of …

Fabrication of reinforced scaffolds for bone regeneration remains a significant challenge.
The weak mechanical properties of the chitosan (CS)-based composite scaffold hindered its …

Background aims To facilitate artificial bone construct integration into a patient's body,
scaffolds are enriched with different biologically active molecules. Among various scaffold …

Traumatic injury or surgical excision of diseased bone tissue usually require the
reconstruction of large bone defects unable to heal spontaneously, especially in older …

Designing biomimetic biomaterials inspired by the natural complex structure of bone and
other hard tissues is still a challenge nowadays. The control of the biomineralization process …

The mimesis of biological systems has been demonstrated to be an adequate approach to
obtain tissue engineering scaffolds able to promote cell attachment, proliferation, and …