Spheroids-on-a-chip: Recent advances and design considerations in microfluidic platforms for spheroid formation and culture
A cell spheroid is a three-dimensional (3D) aggregation of cells. Synthetic, in-vitro spheroids
provide similar metabolism, proliferation, and species concentration gradients to those found …
provide similar metabolism, proliferation, and species concentration gradients to those found …
Microfluidics‐Based Urine Biopsy for Cancer Diagnosis: Recent Advances and Future Trends
Y Wang, Y Gao, Y Song - ChemMedChem, 2022 - Wiley Online Library
Urine biopsy, allowing for the detection, analysis and monitoring of numerous cancer‐
associated urinary biomarkers to provide insights into cancer occurrence, progression and …
associated urinary biomarkers to provide insights into cancer occurrence, progression and …
An on-chip imaging droplet-sorting system: a real-time shape recognition method to screen target cells in droplets with single cell resolution
A microfluidic on-chip imaging cell sorter has several advantages over conventional cell
sorting methods, especially to identify cells with complex morphologies such as clusters …
sorting methods, especially to identify cells with complex morphologies such as clusters …
A microfluidic platform integrated with field-effect transistors for enumeration of circulating tumor cells
Circulating tumor cells (CTCs) are one of the promising cancer biomarkers whose
concentrations are measured not only in the initial diagnostic stages, but also as treatment …
concentrations are measured not only in the initial diagnostic stages, but also as treatment …
A microfluidic platform for high-purity separating circulating tumor cells at the single-cell level
K Wang, L Zhou, S Zhao, Z Cheng, S Qiu, Y Lu, Z Wu… - Talanta, 2019 - Elsevier
Circulating tumor cells (CTCs) are rare cancer cells that are shed from the tumors into the
peripheral blood and are instrumental in distant metastasis. Early detection of CTCs can …
peripheral blood and are instrumental in distant metastasis. Early detection of CTCs can …
Advances in quantitative biology methods for studying replicative aging in Saccharomyces cerevisiae
Aging is a complex, yet pervasive phenomenon in biology. As human cells steadily succumb
to the deteriorating effects of aging, so too comes a host of age-related ailments such as …
to the deteriorating effects of aging, so too comes a host of age-related ailments such as …
Trapping and releasing of single microparticles and cells in a microfluidic chip
D Lv, X Zhang, M Xu, W Cao, X Liu, J Deng… - …, 2022 - Wiley Online Library
A microfluidic device was designed and fabricated to capture single microparticles and cells
by using hydrodynamic force and selectively release the microparticles and cells of interest …
by using hydrodynamic force and selectively release the microparticles and cells of interest …
Separation of fine particles and liquid using a physical trapping method via a stepped structure
M Horade, K Misu, T Usagawa, T Yamawaki… - Microsystem …, 2024 - Springer
This study investigated a component separation method using a microfluidic device.
Specifically, we integrated a micron-scale stepped structure, which is a component of a …
Specifically, we integrated a micron-scale stepped structure, which is a component of a …
Confined cell migration and asymmetric hydraulic environments to evaluate the metastatic potential of cancer cells
Y Juste-Lanas, PE Guerrero… - Journal of …, 2022 - asmedigitalcollection.asme.org
Metastasis, a hallmark of cancer development, is also the leading reason for most cancer-
related deaths. Furthermore, cancer cells are highly adaptable to micro-environments and …
related deaths. Furthermore, cancer cells are highly adaptable to micro-environments and …
Efficient low Shear Flow-based trapping of Biological entities
A Sohrabi Kashani, M Packirisamy - Scientific Reports, 2019 - nature.com
Capturing cells or biological entities is an important and challenging step toward in-vitro
studies of cells under a precisely controlled microscale environment. In this work, we have …
studies of cells under a precisely controlled microscale environment. In this work, we have …