[HTML][HTML] Ozone: a natural bioactive molecule with antioxidant property as potential new strategy in aging and in neurodegenerative disorders

C Scassellati, AC Galoforo, C Bonvicini… - Ageing Research …, 2020 - Elsevier
Abstract Systems medicine is founded on a mechanism-based approach and identifies in
this way specific therapeutic targets. This approach has been applied for the transcription …

Ozone-induced neurotoxicity: In vitro and in vivo evidence

A Singh, S Suresh, C Vellapandian - Ageing Research Reviews, 2023 - Elsevier
Together with cities in higher-income nations, it is anticipated that the real global ozone is
rising in densely populated areas of Asia and Africa. This review aims to discuss the …

Harpagide inhibits neuronal apoptosis and promotes axonal regeneration after spinal cord injury in rats by activating the Wnt/β-catenin signaling pathway

Y Rong, W Liu, Z Zhou, F Gong, J Bai, J Fan, L Li… - Brain Research …, 2019 - Elsevier
The neuronal apoptosis program associated with spinal cord injury (SCI) has a severe
impact on spinal cord function, which leads to further secondary and permanent neuronal …

Effects of mild ozonisation on gene expression and nuclear domains organization in vitro

C Scassellati, M Costanzo, B Cisterna, A Nodari… - Toxicology in vitro, 2017 - Elsevier
In the last two decades, the use of ozone (O 3) as a complementary medical approach has
progressively been increasing; however, its application is still limited due to the numerous …

Does decompressive duraplasty have a neuroprotective effect on spinal trauma?: an experimental study

M Camlar, Ç Turk, A Buhur, F Oltulu, M Oren… - World Neurosurgery, 2019 - Elsevier
Background Spinal cord injury (SCI) may result in neuromotor, sensory, and autonomic
function damages. Edema because of spinal cord trauma can reach serious dimensions …

MicroRNA‑381/Hes1 is a potential therapeutic target for spinal cord injury

W Ruan, G Ning, S Feng, S Gao… - … Journal of Molecular …, 2018 - spandidos-publications.com
The aim of the present study was to investigate whether microRNA-381 is a potential
therapeutic target for spinal cord injury (SCI) and its possible mechanism. Reverse …

Neuroprotective Effects of Coenzyme Q10 and Ozone Therapy on Experimental Traumatic Spinal Cord Injuries in Rats

G Gel, C Unluer, ER Yılmaz, BI Erguder, AT Arıkok… - World Neurosurgery, 2024 - Elsevier
Objective This study investigates the neuroprotective effects and functional recovery
potential of Coenzyme Q10 (CoQ10) and ozone therapy in spinal cord injury (SCI). Material …

Improved spinal cord gray matter morphology induced by Spirulina platensis following spinal cord injury in rat models

D Abdullahi, A Ahmad Annuar, J Sanusi - Ultrastructural Pathology, 2020 - Taylor & Francis
Despite intense preclinical research focusing on developing potential strategies of mitigating
spinal cord injury (SCI), SCI still results in permanent, debilitating symptoms for which there …

[PDF][PDF] 瑞香素对脊髓损伤大鼠运动功能改善作用的TRL4/NF-κB 信号通路机制研究

吴军, 关涛, 田峰, 刘学起, 马剑, 王庆峰… - 中国比较医学 …, 2021 - zgbjyx.cnjournals.com
瑞香素对脊髓损伤大鼠运动功能改善作用的TRL4/ NF-κB 信号通路机制研究 Page 1 2021 年4
月 第31 卷第4 期 中国比较医学杂志 CHINESE JOURNAL OF COMPARATIVE MEDICINE …

[PDF][PDF] Letter to the Editor Regarding" Neuroprotective Effects of Coenzyme Q10 and Ozone Therapy on Experimental Traumatic Spinal Cord Injuries in Rats"

S Chirumbolo, M Franzini, U Tirelli, S Pandolfi… - World …, 2024 - researchgate.net
The recent article by Gel et al., 1 in this Journal, reported the neuroprotective role of ozone,
along with coenzyme Q10 in spinal cord injury. The association of ozone with coenzyme …