[HTML][HTML] Profound properties of protein-rich, platelet-rich plasma matrices as novel, multi-purpose biological platforms in tissue repair, regeneration, and wound …
Autologous platelet-rich plasma (PRP) preparations are prepared at the point of care.
Centrifugation cellular density separation sequesters a fresh unit of blood into three main …
Centrifugation cellular density separation sequesters a fresh unit of blood into three main …
Material matters: exploring the interplay between natural biomaterials and host immune system
AS Tripathi, MEA Zaki, SA Al-Hussain… - Frontiers in …, 2023 - frontiersin.org
Biomaterials are widely used for various medical purposes, for instance, implants, tissue
engineering, medical devices, and drug delivery systems. Natural biomaterials can be …
engineering, medical devices, and drug delivery systems. Natural biomaterials can be …
[HTML][HTML] 3D bioprinting of human neural tissues with functional connectivity
Probing how human neural networks operate is hindered by the lack of reliable human
neural tissues amenable to the dynamic functional assessment of neural circuits. We …
neural tissues amenable to the dynamic functional assessment of neural circuits. We …
Targeted treatment of ischemic and fibrotic complications of myocardial infarction using a dual-delivery microgel therapeutic
Myocardial infarction (MI), commonly known as a heart attack, affects millions of people
worldwide and results in significant death and disabilities. A major cause of MI is fibrin-rich …
worldwide and results in significant death and disabilities. A major cause of MI is fibrin-rich …
Fibrin as a multipurpose physiological platform for bone tissue engineering and targeted delivery of bioactive compounds
B Bujoli, JC Scimeca, E Verron - Pharmaceutics, 2019 - mdpi.com
Although bone graft is still considered as the gold standard method, bone tissue engineering
offers promising alternatives designed to mimic the extracellular matrix (ECM) and to guide …
offers promising alternatives designed to mimic the extracellular matrix (ECM) and to guide …
Clot-Targeted Nanogels for Dual-Delivery of AntithrombinIII and Tissue Plasminogen Activator to Mitigate Disseminated Intravascular Coagulation Complications
A Sheridan, K Nellenbach, S Pandit, E Byrnes… - ACS …, 2024 - ACS Publications
Disseminated intravascular coagulation (DIC) is a pathologic state that follows systemic
injury and other diseases. Often a complication of sepsis or trauma, DIC causes …
injury and other diseases. Often a complication of sepsis or trauma, DIC causes …
Clot structure and implications for bleeding and thrombosis
The formation of a fibrin clot matrix plays a critical role in promoting hemostasis and wound
healing. Fibrin dynamics can become disadvantageous in the formation of aberrant …
healing. Fibrin dynamics can become disadvantageous in the formation of aberrant …
Biologic principles of minced cartilage implantation: a narrative review
R Ossendorff, SG Walter, FA Schildberg… - Archives of Orthopaedic …, 2023 - Springer
Cartilage tissue has a very limited ability to regenerate. Symptomatic cartilage lesions are
currently treated by various cartilage repair techniques. Multiple treatment techniques have …
currently treated by various cartilage repair techniques. Multiple treatment techniques have …
Differential sialic acid content in adult and neonatal fibrinogen mediates differences in clot polymerization dynamics
Neonates possess a molecular variant of fibrinogen, known as fetal fibrinogen,
characterized by increased sialic acid, a greater negative charge, and decreased activity …
characterized by increased sialic acid, a greater negative charge, and decreased activity …
Fibrin nanoparticles coupled with keratinocyte growth factor enhance the dermal wound-healing rate
Expediting the wound-healing process is critical for patients chronically ill from nonhealing
wounds and diseases such as hemophilia or diabetes or who have suffered trauma …
wounds and diseases such as hemophilia or diabetes or who have suffered trauma …