Artemisinin (ART) is a bioactive compound isolated from the plant Artemisia annua and has
been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial …

Background Electrocardiographic QT interval prolongation is the most widely used risk
marker for ventricular arrhythmia potential and thus an important component of drug …

The objective of this study was to develop solid solution (SSL) using hot-melt extrusion as a
continuous manufacturing method. Powder blends of artesunate (ARS) a water insoluble …

Abstract Background The Drugs for Neglected Diseases initiative (DND i) is a not-for profit
organization committed to providing affordable medicines and access to treatments in …

Over the last few years, Pharmacokinetics has emerged as an integral part of drug
development, especially when identifying a drug's biological properties. Understanding of …

In the last one decade, due to expiry of patented products as well as their exclusivity period,
a drastic decline of branded pharmaceutical products and up streaming of generic drug …

Background The determination of dosing regimens for the treatment of malaria is largely
empirical and thus a better understanding of the pharmacokinetic/pharmacodynamic …

Bioavailability is a pharmacokinetic term which refers the extent and speed of absorption of
the chemicals content in it. After the absorption the drug plays the important role in which the …

Antibiotics are an efficient means of treating bacterial infections. They help in the reduction
of mortality and morbidity. Discovery of antibiotic has created a new epoch where infectious …

Malaria is a parasite with a complex lifecycle, and commonly used antimalarial agents from
the artemisinin family have varied effectiveness over different stages of this lifecycle. The …