Although neuromuscular adverse effects represent significant clinical manifestations of
hypervitaminosis A syndrome, surprisingly little attention has been paid to the potential …

Background: Isotretinoin is frequently used for treatment of severe nodulocystic and
papulopustular acne, however use is limited by mucocutaneous, ocular, and systemic side …

Background: Oral isotretinoin treatment can cause ocular side effects. Objective: This study
was performed to detect possible toxic effects of oral isotretinoin treatment on the retinal …

Purpose: To investigate the effects of systemic isotretinoin therapy on retina by measuring
retinal nerve fiber layer (RNFL) and macular thicknesses. Method: This prospective, cross …

Purpose: To evaluate the long-term effect of oral isotretinoin therapy on macula ganglion cell
complex (GCC) thickness by spectral domain optical coherence tomography (SD-OCT) …

To evaluate the effect of oral isotretinoin therapy on retinal nerve fiber layer (RNFL) and
ganglion cell layer (GCL) thickness by spectral domain optical coherence tomography …

Introduction Central nervous system toxicity is a well-known side effect of isotretinoin
treatment. The aim of this study was to establish the effects of isotretinoin on retinal nerve …

Aim The purpose of this prospective study is to investigate the effect of oral isotretinoin
therapy on auditory function using pure tone audiometry (PTA) and distortion product …

Isotretinoin is widely used in the treatment of extensive and nodulocystic acne. The objective
of this prospective study was to investigate whether oral isotretinoin could affect the hearing …

A causal association between central nervous system neuropathy and oral isotretinoin has
been reported. In this study we aimed to assess retinal nerve fibre layer (RNFL) thickness …