Inotrope and vasopressor use in cardiogenic shock: what, when and why?

K Hu, R Mathew - Current Opinion in Critical Care, 2022 - journals.lww.com
Review of the current literature fails to show significant mortality benefit with any specific
vasopressor or inotropic in CS patients. The upcoming DOREMI 2 and levosimendan versus …

[HTML][HTML] Transcatheter edge-to-edge repair in patients with mitral regurgitation and cardiogenic shock: a new therapeutic target

RG Jung, T Simard, P Di Santo… - Current Opinion in …, 2022 - journals.lww.com
TEER remains a promising therapeutic option in cardiogenic shock complicated by
significant mitral regurgitation, but additional research is required to identify patient and …

Lactate clearance as a surrogate for mortality in cardiogenic shock: insights from the DOREMI trial

JA Marbach, P Di Santo, NK Kapur… - Journal of the …, 2022 - Am Heart Assoc
Background Recent studies have shown improved outcomes in cardiogenic shock through
protocols directed toward early identification and initiation of mechanical circulatory support …

Significant valvular dysfunction and outcomes in cardiogenic shock: insights from the randomized DOREMI trial

S Parlow, W Weng, P Di Santo, RG Jung… - Canadian Journal of …, 2022 - Elsevier
Background Patients with cardiogenic shock (CS) suffer high rates of in-hospital mortality,
with little evidence guiding management. The impact of valvular heart disease in patients …

[HTML][HTML] Beta-blocker management in patients admitted for acute heart failure and reduced ejection fraction: a review and expert consensus opinion

G Schurtz, N Mewton, G Lemesle, C Delmas… - Frontiers in …, 2023 - frontiersin.org
The role of the beta-adrenergic signaling pathway in heart failure (HF) is pivotal. Early
blockade of this pathway with beta-blocker (BB) therapy is recommended as the first-line …

Medical therapy of cardiogenic shock: Contemporary use of inotropes and vasopressors

M Riccardi, M Pagnesi, O Chioncel… - European Journal of …, 2024 - Wiley Online Library
Cardiogenic shock is a primary cardiac disorder that results in both clinical and biochemical
evidence of tissue hypoperfusion and can lead to multi‐organ failure and death depending …

[HTML][HTML] Efficacy of milrinone and dobutamine in cardiogenic shock: an updated systematic review and meta-analysis

O Abdel-Razek, P Di Santo, RG Jung… - Critical Care …, 2023 - journals.lww.com
OBJECTIVES: Inotropic support is commonly used in patients with cardiogenic shock (CS).
High-quality data guiding the use of dobutamine or milrinone among this patient population …

[HTML][HTML] No sex-based difference in cardiogenic shock: A post-hoc analysis of the DOREMI trial

G Prosperi-Porta, P Motazedian, P Di Santo… - Journal of …, 2022 - Elsevier
Background Cardiogenic shock (CS) is associated with significant morbidity and mortality;
however, there are limited randomized data evaluating the association between sex and …

[HTML][HTML] Inotropic support in cardiogenic shock: who leads the battle, milrinone or dobutamine?

IDL Martinez, AJ Bayona-Gamboa… - Annals of Medicine and …, 2022 - Elsevier
Cardiovascular diseases remain the leading cause of death globally, with acute myocardial
infarction being one of the most frequent. One of the complications that can occur after a …

Meta-analysis comparing the efficacy of dobutamine versus milrinone in acute decompensated heart failure and cardiogenic shock

S Biswas, AH Malik, D Bandyopadhyay, R Gupta… - Current Problems in …, 2023 - Elsevier
This study aims to evaluate the difference between dobutamine and milrinone in patients
presenting with acute decompensated heart failure (AHF). Inotropes are indicated for …