Pharmacokinetics of snake venom

S Sanhajariya, SB Duffull, GK Isbister - Toxins, 2018 - mdpi.com
Understanding snake venom pharmacokinetics is essential for developing risk assessment
strategies and determining the optimal dose and timing of antivenom required to bind all …

Snakebite: When the human touch becomes a bad touch

BG Fry - Toxins, 2018 - mdpi.com
Many issues and complications in treating snakebite are a result of poor human social,
economic and clinical intervention and management. As such, there is scope for significant …

Coral snake bites (Micrurus spp.) in Brazil: a review of literature reports

F Bucaretchi, EM De Capitani, RJ Vieira… - Clinical …, 2016 - Taylor & Francis
Abstract Context: In the Americas, the main representatives of the family Elapidae are coral
snakes of the genus Micrurus, of which 33 species are in Brazil. They are the smallest cause …

Recent developments in diagnostic tools and bioanalytical methods for analysis of snake venom: A critical review

U Puzari, AK Mukherjee - Analytica Chimica Acta, 2020 - Elsevier
Snakebite is a neglected medical emergency causing fatalities and long-term disabilities
throughout the world, especially in tropical countries. The effectiveness of therapy against …

Eastern coral snake Micrurus fulvius venom toxicity in mice is mainly determined by neurotoxic phospholipases A2

I Vergara, M Pedraza-Escalona, D Paniagua… - Journal of …, 2014 - Elsevier
Here we show for the first time that the venom from an elapid (Micrurus fulvius) contains
three finger toxin (3FTxs) peptides with low toxicity but high content of lethal phospholipases …

Time-resolved MRI assessment of convection-enhanced delivery by targeted and nontargeted nanoparticles in a human glioblastoma mouse model

ZR Stephen, PA Chiarelli, RA Revia, K Wang, F Kievit… - Cancer research, 2019 - AACR
Convection-enhanced delivery (CED) provides direct access of infusates to brain tumors;
however, clinical translation of this technology has not been realized because of the inability …

In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model

M Benard-Valle, Y Wouters, A Ljungars… - Nature …, 2024 - nature.com
Oligoclonal mixtures of broadly-neutralizing antibodies can neutralize complex compositions
of similar and dissimilar antigens, making them versatile tools for the treatment of eg …

Lymphatic vessel pumping

PY von der Weid - Smooth Muscle Spontaneous Activity: Physiological …, 2019 - Springer
The lymphatic system extends its network of vessels throughout most of the body. Lymphatic
vessels carry a fluid rich in proteins, immune cells, and long-chain fatty acids known as …

Effect of the snake venom component crotamine on lymphatic endothelial cell responses and lymph transport

H Si, C Yin, W Wang, P Davies, E Sanchez… - …, 2023 - Wiley Online Library
Objective The pathology of snake envenomation is closely tied to the severity of edema in
the tissue surrounding the area of the bite. Elucidating the mechanisms that promote the …

Snake Antivenoms—Toward Better Understanding of the Administration Route

E Gamulin, S Mateljak Lukačević, B Halassy, T Kurtović - Toxins, 2023 - mdpi.com
Envenomations induced by animal bites and stings constitute a significant public health
burden. Even though a standardized protocol does not exist, parenterally administered …