Natriuretic peptides, brain (B-type) natriuretic peptide (BNP) and N-terminal prohormone of
brain natriuretic peptide (NT-proBNP) are globally and most often used for the diagnosis of …

The global prevalence of obesity has more than doubled over the past four decades,
currently affecting more than a billion individuals. Beyond its recognition as a high-risk …

Recently, the 4th Universal Definition of Myocardial Infarction was published. 1 Perhaps it is
time to consider a First Universal Definition of Heart Failure. Objective, clinically verifiable …

Although patients with heart failure with preserved ejection fraction (HFpEF)(left ventricular
ejection fraction≥ 50%) comprise nearly half of those with chronic heart failure, evidence …

The discovery of the heart as an endocrine organ resulted in a remarkable recognition of the
natriuretic peptide system (NPS). Specifically, research has established the production of …

Abstract Background Phenylacetylglutamine (PAGln)—a newly discovered microbial
metabolite produced by phenylalanine metabolism—is reportedly associated with …

Increasing evidence suggests natriuretic peptides (NPs) coordinate inter-organ metabolic
crosstalk with adipose tissues and play a critical role in energy metabolism. We recently …

Abstract Background This Obesity Medicine Association (OMA) Clinical Practice Statement
(CPS) provides an overview of the mechanisms and treatment of obesity and hypertension …

Heart failure with preserved ejection fraction (HFpEF) is increasingly recognised and
diagnosed in clinical practice, a trend driven by an ageing population and a rise in …

Measurement of natriuretic peptides (NPs) has proven its clinical value as biomarker,
especially in the context of heart failure (HF). In contrast, a state of partial NP deficiency …