Ticks and the pathogens they transmit constitute a growing burden for human and animal
health worldwide. Vector competence is a component of vectorial capacity and depends on …

The remarkable gene knockdown technique of RNAi has opened exciting new avenues for
genetic screens in model organisms and human cells. Here we describe the current state of …

Malaria-transmitting mosquitoes are continuously exposed to microbes, including their
midgut microbiota. This naturally acquired microbial flora can modulate the mosquito's …

Mosquito midgut invasion by ookinetes of the malaria parasite Plasmodium disrupts the
barriers that normally prevent the gut microbiota from coming in direct contact with epithelial …

Mosquitoes transmit numerous pathogens, but large gaps remain in our understanding of
their physiology. To facilitate explorations of mosquito biology, we have created Aegypti …

Nearly one million people are killed every year by the malaria parasite Plasmodium.
Although the disease-causing forms of the parasite exist only in the human blood …

The mosquito midgut is a hostile environment that vector‐borne parasites must survive to be
transmitted. Commensal bacteria in the midgut can reduce the ability of mosquitoes to …

Transmission of malaria is dependent on the successful completion of the Plasmodium
lifecycle in the Anopheles vector. Major obstacles are encountered in the midgut tissue …

Activation of the insect innate immune system is dependent on a limited number of pattern
recognition receptors (PRRs) capable of interacting with pathogen-associated molecular …

The involvement of reactive oxygen species (ROS) in mosquito immunity against bacteria
and Plasmodium was investigated in the malaria vector Anopheles gambiae. Strains of An …