3D printing technologies in personalized medicine, nanomedicines, and biopharmaceuticals
3D printing technologies enable medicine customization adapted to patients' needs. There
are several 3D printing techniques available, but majority of dosage forms and medical …
are several 3D printing techniques available, but majority of dosage forms and medical …
Advancing frontiers in bone bioprinting
N Ashammakhi, A Hasan, O Kaarela… - Advanced …, 2019 - Wiley Online Library
Abstract Three‐dimensional (3D) bioprinting of cell‐laden biomaterials is used to fabricate
constructs that can mimic the structure of native tissues. The main techniques used for 3D …
constructs that can mimic the structure of native tissues. The main techniques used for 3D …
Organ‐on‐chip models: implications in drug discovery and clinical applications
R Mittal, FW Woo, CS Castro, MA Cohen… - Journal of cellular …, 2019 - Wiley Online Library
Before a lead compound goes through a clinical trial, preclinical studies utilize two‐
dimensional (2D) in vitro models and animal models to study the pharmacodynamics and …
dimensional (2D) in vitro models and animal models to study the pharmacodynamics and …
[HTML][HTML] Cardiovascular disease models: a game changing paradigm in drug discovery and screening
H Savoji, MH Mohammadi, N Rafatian, MK Toroghi… - Biomaterials, 2019 - Elsevier
Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …
drug discovery and development has been sky-rocketing, the number of approved drugs has …
3D bioprinted organ‐on‐chips
S Rahmani Dabbagh, M Rezapour Sarabi… - …, 2023 - Wiley Online Library
Abstract Organ‐on‐a‐chip (OOC) platforms recapitulate human in vivo‐like conditions more
realistically compared to many animal models and conventional two‐dimensional cell …
realistically compared to many animal models and conventional two‐dimensional cell …
3D cell cultures: Evolution of an ancient tool for new applications
A Cacciamali, R Villa, S Dotti - Frontiers in Physiology, 2022 - frontiersin.org
Recently, research is undergoing a drastic change in the application of the animal model as
a unique investigation strategy, considering an alternative approach for the development of …
a unique investigation strategy, considering an alternative approach for the development of …
Nanocomposite bioprinting for tissue engineering applications
Bioprinting aims to provide new avenues for regenerating damaged human tissues through
the controlled printing of live cells and biocompatible materials that can function …
the controlled printing of live cells and biocompatible materials that can function …
Tumor heterogeneity: preclinical models, emerging technologies, and future applications
Heterogeneity describes the differences among cancer cells within and between tumors. It
refers to cancer cells describing variations in morphology, transcriptional profiles …
refers to cancer cells describing variations in morphology, transcriptional profiles …
Multi-organs-on-chips: towards long-term biomedical investigations
Y Zhao, RK Kankala, SB Wang, AZ Chen - Molecules, 2019 - mdpi.com
With advantageous features such as minimizing the cost, time, and sample size
requirements, organ-on-a-chip (OOC) systems have garnered enormous interest from …
requirements, organ-on-a-chip (OOC) systems have garnered enormous interest from …
The emergence of 3D bioprinting in organ-on-chip systems
Understanding complex cell–cell interactions and physiological microenvironments is critical
for the development of new therapies for treating human diseases. Current animal models …
for the development of new therapies for treating human diseases. Current animal models …