Molecular subtypes of pancreatic cancer

EA Collisson, P Bailey, DK Chang… - Nature reviews …, 2019 - nature.com
Cancers that appear morphologically similar often have dramatically different clinical
features, respond variably to therapy and have a range of outcomes. Compelling evidence …

Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas

M Tanaka, C Fernández-del Castillo, T Kamisawa… - Pancreatology, 2017 - Elsevier
The management of intraductal papillary mucinous neoplasm (IPMN) continues to evolve. In
particular, the indications for resection of branch duct IPMN have changed from early …

KRAS: the critical driver and therapeutic target for pancreatic cancer

AM Waters, CJ Der - Cold Spring Harbor …, 2018 - perspectivesinmedicine.cshlp.org
RAS genes (HRAS, KRAS, and NRAS) comprise the most frequently mutated oncogene
family in human cancer. With the highest RAS mutation frequencies seen with the top three …

A revised classification system and recommendations from the Baltimore consensus meeting for neoplastic precursor lesions in the pancreas

O Basturk, SM Hong, LD Wood, NV Adsay… - The American journal …, 2015 - journals.lww.com
International experts met to discuss recent advances and to revise the 2004
recommendations for assessing and reporting precursor lesions to invasive carcinomas of …

International evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas

T Ohtsuka, C Fernandez-del Castillo, T Furukawa… - Pancreatology, 2023 - Elsevier
This study group aimed to revise the 2017 international consensus guidelines for the
management of intraductal papillary mucinous neoplasm (IPMN) of the pancreas, and …

International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas

M Tanaka, C Fernández-del Castillo, V Adsay, S Chari… - Pancreatology, 2012 - Elsevier
The international consensus guidelines for management of intraductal papillary mucinous
neoplasm and mucinous cystic neoplasm of the pancreas established in 2006 have …

Pancreatic cancer

A Vincent, J Herman, R Schulick, RH Hruban… - The lancet, 2011 - thelancet.com
Substantial progress has been made in our understanding of the biology of pancreatic
cancer, and advances in patients' management have also taken place. Evidence is …

[HTML][HTML] Artificial intelligence and early detection of pancreatic cancer: 2020 summative review

B Kenner, ST Chari, D Kelsen, DS Klimstra, SJ Pandol… - Pancreas, 2021 - journals.lww.com
Despite considerable research efforts, pancreatic cancer is associated with a dire prognosis
and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly …

Frequent detection of pancreatic lesions in asymptomatic high-risk individuals

MI Canto, RH Hruban, EK Fishman, IR Kamel… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: The risk of pancreatic cancer is increased in patients with a strong
family history of pancreatic cancer or a predisposing germline mutation. Screening can …

Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas

T Furukawa, Y Kuboki, E Tanji, S Yoshida, T Hatori… - Scientific reports, 2011 - nature.com
Intraductal papillary mucinous neoplasm (IPMN) is a common pancreatic cystic neoplasm
that is often invasive and metastatic, resulting in a poor prognosis. Few molecular alterations …