Pheochromocytomas (PHEOs) are rare neuroendocrine tumors that arise from the
chromaffin cells of the adrenal glands. Paragangliomas (PGLs), the extra-adrenal …

Succinate dehydrogenase (SDH) mutations lead to the accumulation of succinate, which
acts as an oncometabolite. Germline SDHx mutations predispose to paraganglioma (PGL) …

Heat shock proteins (HSPs) are the molecular chaperones, that are not only expressed
during the normal growth process of cell cycle consecutively, but also get induced in cells …

The treatment of hormone hypersecretory syndromes caused by neuroendocrine tumors
(NETs) can be a major challenge. NETs originating from the small intestine often secrete …

Heat shock proteins (HSPs) belong to a superfamily of stress proteins that are critical
constituents of a complex defense mechanism that enhances cell survival under adverse …

Background Ovarian cancer is a common gynecologic malignancy with poor prognosis,
requiring innovative new therapeutic strategies. Temperature-controlled drug delivery to …

Pheochromocytomas and paragangliomas (PPGLs) are tumors arising from the adrenal
medulla and sympathetic/parasympathetic paraganglia, respectively. According to Th e …

Warburg's metabolic hypothesis is based on the assumption that a cancer cell's respiration
must be under attack, leading to its damage, in order to obtain increased glycolysis …

Prostate cancer metastasis is a significant cause of mortality in men. PKD3 facilitates tumor
growth and metastasis, however, its regulation is largely unclear. The Hsp90 chaperone …

Pheochromocytoma and paraganglioma (PCC/PGL) are rare tumors that originate from
adrenal or extra-adrenal chromaffin cells. A significant clinical manifestation of PCC/PGL is …