The role of praziquantel in the prevention and treatment of fibrosis associated with schistosomiasis: a review

X Niu, T Hu, Y Hong, X Li, Y Shen - Journal of Tropical …, 2022 - Wiley Online Library
Schistosomiasis remains a major global public health concern. Currently, the control of this
neglected tropical disease still depends on chemotherapy to reduce the prevalence and …

A dual drug-loaded peptide system with morphological transformation prolongs drug retention and inhibits breast cancer growth

X Zhai, S Tang, F Meng, J Ma, A Li, X Zou, B Zhou… - Biomaterials …, 2023 - Elsevier
The treatment of breast cancer relies heavily on chemotherapy, but chemotherapy is limited
by the disadvantages of poor targeting, susceptibility to extracellular matrix (ECM) …

Losartan-IR820-Loaded Polydopamine Nanoparticles for CO2-Generating Ultrasound Imaging-Guided Photothermal/Photodynamic Therapies of Triple-Negative …

X Chen, G Li, S Dai, Q Li, Q Jiang, S Ou… - ACS Applied Nano …, 2023 - ACS Publications
Constructing efficient theranostic nanoparticles (NPs) to improve the therapeutic effect is a
great challenge for triple-negative breast cancer (TNBC). Theranostic NPs fail to reach an …

Telmisartan, an AT1 receptor blocker and a PPAR gamma activator, alleviates liver fibrosis induced experimentally by Schistosoma mansoni infection

YM Attia, EF Elalkamy, OA Hammam, SS Mahmoud… - Parasites & vectors, 2013 - Springer
Background Hepatic schistosomiasis is considered to be one of the most prevalent forms of
chronic liver disease in the world due to its complication of liver fibrosis. The demonstration …

Melanin-like nanoparticles loaded with an angiotensin antagonist for an improved photothermal cancer therapy

Z Zhou, Y Yan, Q Zhang, Y Cheng - Biomaterials science, 2020 - pubs.rsc.org
An abnormal tumor growth induces solid stress in tumors, thus reducing blood perfusion. As
a result, the impaired blood perfusion, with dense interstitial matrix in tumors significantly …

MicroRNA-181b promotes schistosomiasis-induced hepatic fibrosis by targeting Smad7

S Wang, J Zhang, H Chen, X Zhan, H Nie… - Molecular and …, 2022 - Elsevier
Schistosomiasis is a common parasitic disease. Hepatosplenic schistosomiasis, caused by
Schistosoma japonicum and Schistosoma mansoni, involves pathological changes …

[HTML][HTML] Establishment of a hepatic cirrhosis and portal hypertension model by hepatic arterial perfusion with 80% alcohol

L Wang, FL He, FQ Liu, ZD Yue… - World Journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To determine the feasibility and safety of establishing a porcine hepatic cirrhosis and
portal hypertension model by hepatic arterial perfusion with 80% alcohol. METHODS …

The comparative efficacy of renin-angiotensin system blockers in schistosomal hepatic fibrosis

NA Parreira, FS Ramalho, MJ Augusto, DM Silva… - Experimental …, 2018 - Elsevier
Schistosomiasis mansoni is involved in hepatic fibrogenesis and portal hypertension.
Previous studies proved that blockade of some components of the renin-angiotensin system …

[HTML][HTML] Superimposing a high-fat diet on Schistosoma mansoni infection affects renin-angiotensin system components in the mouse kidney

DGD Lira, DC Oliveira, FA Brayner, AL Aires… - Revista da Sociedade …, 2019 - SciELO Brasil
INTRODUCTION: The levels of the full-length form of the (pro) renin receptor (PRR), a
component of the renin-angiotensin system (RAS), may be reduced in the membranes of …

[PDF][PDF] Major Article

DGD Lira, DC de Oliveira, FA Brayner… - Journal of the Brazilian …, 2019 - academia.edu
Introduction: The levels of the full-length form of the (pro) renin receptor (PRR), a component
of the renin-angiotensin system (RAS), may be reduced in the membranes of kidneys in …