Reciprocal regulation of mitochondrial fission and fusion

R Sabouny, TE Shutt - Trends in biochemical sciences, 2020 - cell.com
The dynamic processes of mitochondrial fission and fusion are tightly regulated, determine
mitochondrial shape, and influence mitochondrial functions. For example, fission and fusion …

[HTML][HTML] Regulation of mammalian mitochondrial dynamics: opportunities and challenges

R Yu, U Lendahl, M Nistér, J Zhao - Frontiers in endocrinology, 2020 - frontiersin.org
Mitochondria are highly dynamic organelles and important for a variety of cellular functions.
They constantly undergo fission and fusion events, referred to as mitochondrial dynamics …

Mechanisms of mitochondrial fission and fusion

AM Van der Bliek, Q Shen… - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
Mitochondria continually change shape through the combined actions of fission, fusion, and
movement along cytoskeletal tracks. The lengths of mitochondria and the degree to which …

Mitochondrial fusion and fission in cell life and death

B Westermann - Nature reviews Molecular cell biology, 2010 - nature.com
Mitochondria are dynamic organelles that constantly fuse and divide. These processes
(collectively termed mitochondrial dynamics) are important for mitochondrial inheritance and …

[HTML][HTML] Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and …

W Li, MH Bengtson, A Ulbrich, A Matsuda, VA Reddy… - PloS one, 2008 - journals.plos.org
Specificity of protein ubiquitylation is conferred by E3 ubiquitin (Ub) ligases. We have
annotated∼ 617 putative E3s and substrate-recognition subunits of E3 complexes encoded …

The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells

S Gandre-Babbe, AM van der Bliek - Molecular biology of the cell, 2008 - Am Soc Cell Biol
Few components of the mitochondrial fission machinery are known, even though
mitochondrial fission is a complex process of vital importance for cell growth and survival …

The machines that divide and fuse mitochondria

S Hoppins, L Lackner, J Nunnari - Annu. Rev. Biochem., 2007 - annualreviews.org
Mitochondria are derived from eubacteria; however, in most eukaryotes, novel mechanisms
for the propagation of this organelle and its genome have evolved. This review focuses on …

Control of mitochondrial biogenesis and function by the ubiquitin–proteasome system

P Bragoszewski, M Turek, A Chacinska - Open biology, 2017 - royalsocietypublishing.org
Mitochondria are pivotal organelles in eukaryotic cells. The complex proteome of
mitochondria comprises proteins that are encoded by nuclear and mitochondrial genomes …

Determinants and functions of mitochondrial behavior

K Labbé, A Murley, J Nunnari - Annual review of cell and …, 2014 - annualreviews.org
Mitochondria are ancient organelles evolved from bacteria. Over the course of evolution, the
behavior of mitochondria inside eukaryotic cells has changed dramatically, and the …

Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes

K Okamoto, JM Shaw - Annu. Rev. Genet., 2005 - annualreviews.org
Mitochondria form dynamic tubular networks that continually change their shape and move
throughout the cell. In eukaryotes, these organellar gymnastics are controlled by numerous …