Mass spectrometry has become the method of choice for the qualitative and quantitative
characterization of protein mixtures isolated from all kinds of living organisms. The raw data …

Introduction: The emergence of multidrug-resistant microorganisms has necessitated a
search for new antimicrobial agents. Skin secretions of many frog species contain peptides …

The review describes methods of de novo sequencing of peptides by mass spectrometry. De
novo methods utilize computational approaches to deduce the sequence or partial …

Disulfide-rich peptide venoms from animals such as snakes, spiders, scorpions, and certain
marine snails represent one of nature's great diversity libraries of bioactive molecules. The …

An efficient approach to easy and reliable differentiation between isomeric leucine and
isoleucine in peptide sequencing utilizes multistage electron transfer dissociation and …

Heterogeneity in immune defense effectors can benefit hosts encountering a variety of
parasites and pathogens. Antimicrobial peptides (AMPs) are a diverse set of immune …

Amphibians are one of the oldest classes of vertebrates inhabiting the Earth. Meanwhile, the
only weapon their majority possess involves exclusively peptide cocktail secreted by their …

Amphibian skin secretion has great potential for drug discovery and contributes hundreds of
bioactive peptides including bradykinin-related peptides (BRPs). More than 50 BRPs have …

The present review covers available results on the application of FT‐MS for the de novo
sequencing of natural peptides of various animals: cones, bees, snakes, amphibians …

Delayed wound healing is a persistent medical problem mainly caused by decreased
angiogenesis. Esculentin-1a (1–21) NH 2 [Esc-1a (1–21) NH 2], has broad-spectrum …