Pathological molecular mechanisms involved in myocardial remodeling contribute to alter
the existing structure of the heart, leading to cardiac dysfunction. Among the complex …

Atrial fibrillation (AF) is associated with structural, electrical, and contractile remodeling of
the atria. Development and progression of atrial fibrosis is the hallmark of structural …

Cardiotoxicity has emerged as a major side effect of doxorubicin (DOX) treatment, affecting
nearly 30% of patients within 5 years after chemotherapy. Heart failure is the first non-cancer …

Heart failure is a highly morbid and mortal clinical condition that represents the last stage of
most cardiovascular disorders. Diabetes is strongly associated with an increased incidence …

Overlapping pandemics of lifestyle-related diseases pose a substantial threat to
cardiovascular health. Apart from coronary artery disease, metabolic disturbances linked to …

Neutrophil-to-lymphocyte ratio (NLR) has been associated with poor outcomes in patients
with acute coronary syndromes. However, its role for risk stratification in acute …

The cellular and molecular mechanism involved in the pathogenesis of atrial fibrosis are
highly complex. We have reviewed the literature that covers the effectors, signal transduction …

Heart failure with preserved ejection fraction (HFpEF) is an increasingly studied entity
accounting for 50% of all diagnosed heart failure and that has claimed its own dignity being …

Heart failure (HF) is a multifactorial disorder and is usually the end stage of many
cardiovascular diseases (CVD). HF presents one of the highest morbidity and mortality …

The prevalence of type 2 diabetes (T2D) has reached a pandemic scale. Systemic chronic
inflammation dominates the diabetes pathophysiology and has been implicated as a causal …