▪ Abstract Outer hair cell electromotility is crucial for the amplification, sharp frequency
selectivity, and nonlinearities of the mammalian cochlea. Current modeling efforts based on …

Known as the bible of biomedical engineering, The Biomedical Engineering Handbook,
Fourth Edition, sets the standard against which all other references of this nature are …

Traditionally, applications of biomechanics will model system-level aspects of the human
body. As a result, the majority of technological progress to date appears in system-level …

Optical tweezers were used to characterize the mechanical properties of the outer hair cell
(OHC) plasma membrane by pulling tethers with 4.5-μm polystyrene beads. Tether formation …

In this study, two viscoelastic creep expressions for the aspirated length of individual solid-
like cells undergoing micropipette aspiration (MPA) were derived based on our previous …

Presents Current Principles and Applications Biomedical engineering is considered to be
the most expansive of all the engineering sciences. Its function involves the direct …

The outer hair cell makes both passive and active contributions to basilar membrane
mechanics. The outer hair cell mechanics is strongly coupled to the elastic properties of the …

Tethers are thin membrane tubes that can be formed when relatively small and localized
forces are applied to cellular membranes and lipid bilayers. Tether pulling experiments have …

We analyze the nonlinear behavior of the longitudinal and circumferential components of the
active force generated by the outer hair cell wall in response to changes of its …

Simple three-dimensional passive and active models of the human basilar membrane were
built, solved using the Finite Element Method and tested. In the active model an active …