The recent expansion of next-generation sequencing has significantly improved biological
research. Nevertheless, deep exploration of genomes or metagenomic samples remains …

The pan-genomic microarray technique is used for environmental and/or clinical studies.
Although microarray is an accurate and sharp diagnostic tool, the expertized …

Soil microbial communities contain the highest level of prokaryotic diversity of any
environment, and metagenomic approaches involving the extraction of DNA from soil can …

Emerging spatial profiling technology has enabled high-plex molecular profiling in biological
tissues, preserving the spatial and morphological context of gene expression. Here, we …

The average citizen thinks of microbes as dangerous or at least as nasty enemies to her/his
health that she/he cannot see. The invisibility to the naked eye is the reason why microbes …

Evaluating the composition of the human gut microbiota greatly facilitates studies on its role
in human pathophysiology, and is heavily reliant on culture-independent molecular …

It is the aim of this chapter to present an overview of new, molecular tools that have been
developed over recent years to study individual, single cells and composite, complex …

Background Microorganisms comprise the majority of living organisms on our planet. For
many years, exploration of the composition of microbial communities has been performed …

Designing environmental DNA microarrays that can be used to survey the extreme diversity
of microorganisms existing in nature, represents a stimulating challenge in the field of …

Next-generation sequencing (NGS) allows faster acquisition of metagenomic data, but
complete exploration of complex ecosystems is hindered by the extraordinary diversity of …