Novel paradigms of salt and hypertension

W Feng, LJ Dell'Italia, PW Sanders - Journal of the American …, 2017 - journals.lww.com
Salt resistance/sensitivity refers specifically to the effect of dietary sodium chloride (salt)
intake on BP. Increased dietary salt intake promotes an early and uniform expansion of …

Vascular consequences of dietary salt intake

PW Sanders - American Journal of Physiology-Renal …, 2009 - journals.physiology.org
Animal and human studies support an untoward effect of excess dietary NaCl (salt) intake on
cardiovascular and renal function and life span. Recent work has promoted the concept that …

Mechanisms and consequences of salt sensitivity and dietary salt intake

M Kanbay, Y Chen, Y Solak… - Current opinion in …, 2011 - journals.lww.com
There is growing appreciation that, independently of alterations in blood pressure, dietary
intake of sodium and potassium promotes functional changes in the vasculature and …

Perivascular Adipose Tissue Is a Major Source of Nitric Oxide in Saphenous Vein Grafts Harvested via the No‐Touch Technique

T Saito, H Kurazumi, R Suzuki… - Journal of the …, 2022 - Am Heart Assoc
Background Saphenous vein grafts (SVGs) are broadly used in coronary artery bypass
grafting despite their inferior patency compared with arterial grafts. Recently, the no‐touch …

Dietary salt intake, salt sensitivity, and cardiovascular health

PW Sanders - Hypertension, 2009 - Am Heart Assoc
The controversial issue of the relationship between dietary NaCl (referred to as “salt” in this
article) intake and health was framed nicely in the superb review by Prof Eberhard Ritz. 1 …

Salt, angiotensin II, superoxide, and endothelial function

MA Boegehold, I Drenjancevic… - Comprehensive …, 2011 - Wiley Online Library
Proper function of the vascular endothelium is essential for cardiovascular health, in large
part due to its antiproliferative, antihypertrophic, and anti‐inflammatory properties. Crucial to …

Transforming growth factor-β mediates endothelial dysfunction in rats during high salt intake

W Feng, WZ Ying, KJ Aaron… - American Journal of …, 2015 - journals.physiology.org
Endothelial dysfunction has been shown to be predictive of subsequent cardiovascular
events and death. Through a mechanism that is incompletely understood, increased dietary …

Losartan improves aortic endothelium-dependent relaxation via proline-rich tyrosine kinase 2/Src/Akt pathway in type 2 diabetic Goto-Kakizaki rats

S Nemoto, T Kobayashi, K Taguchi… - American Journal …, 2011 - journals.physiology.org
In diabetic states, endothelial dysfunction is related to vascular complications. We
hypothesized that insulin-induced relaxation and the associated proline-rich tyrosine kinase …

Effect of dietary salt on regulation of TGF-β in the kidney

MB Hovater, PW Sanders - Seminars in nephrology, 2012 - Elsevier
Dietary sodium chloride (salt) has long been considered injurious to the kidney by promoting
the development of glomerular and tubulointerstitial fibrosis. Endothelial cells throughout the …

[HTML][HTML] Pivotal role of apoptosis signal-regulating kinase 1 in monoclonal free light chain–mediated apoptosis

WZ Ying, PX Wang, PW Sanders - The American journal of pathology, 2012 - Elsevier
Renal failure, a major complication associated with multiple myeloma, is usually related to
deposition of monoclonal immunoglobulin free light chains (FLCs) and directly contributes to …