Acne vulgaris is an extraordinarily common skin condition in adolescents. The mainstays of
acne treatment have remained largely unchanged over recent years. In the context of …

Introduction Acne is a chronic, inflammatory, and immune mediated disease of
pilosebaceous unit, highly prevalent in adolescents. It involves face, trunk, and back; may …

Drug-related adverse events or adverse drug reactions (ADRs) are currently partially or
substantially under-reported. ADR reporting systems need to expand their focus to include …

Background: Isotretinoin is a synthetic retinoid, derived from vitamin A, with multiple
mechanisms of action and highly effective in the treatment of acne, despite common adverse …

Importance Although isotretinoin may rarely be associated with laboratory abnormalities
such as hypertriglyceridemia, the optimal approach to laboratory monitoring is uncertain …

Isotretinoin is an oral derivate of vitamin A that has been used since 1982 for the treatment of
multiple dermatologic conditions such as severe acne, rosacea, scarring alopecia …

Acne vulgaris is a chronic inflammatory skin disease with a multifactorial pathogenesis.
Although a variety of acne treatments are available, limitations of current therapies include …

Background Exposure to isotretinoin during pregnancy must be avoided due to its
teratogenicity, but real-world data on its use are scarce. We aimed to describe (i) isotretinoin …

Isotretinoin (ISO) is a powerful vitamin A derivative that offers the potential for treatment of
permanent remission of acne; however, its potential side effects on both physiological and …

Isotretinoin is a first‐generation retinoid initially approved for the treatment of severe cases
of acne vulgaris (nodulocystic acne). Because of its broad anti‐inflammatory and …