A systematic review of the preventive and therapeutic effects of naringin against human malignancies

M Ghanbari-Movahed, G Jackson… - Frontiers in …, 2021 - frontiersin.org
Background: Natural product-based cancer preventive and therapeutic entities, such as
flavonoids and their derivatives, are shown to have a noticeable capability to suppress tumor …

FOXM1: A small fox that makes more tracks for cancer progression and metastasis

MA Khan, P Khan, A Ahmad, M Fatima… - Seminars in Cancer …, 2023 - Elsevier
Transcription factors (TFs) are indispensable for the modulation of various signaling
pathways associated with normal cell homeostasis and disease conditions. Among cancer …

Formulation design, statistical optimization, and in vitro evaluation of a naringenin nanoemulsion to enhance apoptotic activity in A549 lung cancer cells

S Md, NA Alhakamy, HM Aldawsari, M Husain, S Kotta… - Pharmaceuticals, 2020 - mdpi.com
Naringenin (NAR), a flavonoid mainly found in citrus and grapefruits, has proven anti-cancer
activities. However, the poor water solubility and low bioavailability of NAR limits its use as a …

Folic acid-modified dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human lung adencarcinoma

H Wang, L Zheng, C Peng, M Shen, X Shi, G Zhang - Biomaterials, 2013 - Elsevier
We report a new usage of folic acid-modified dendrimer-entrapped gold nanoparticles (Au
DENPs-FA) as nanoprobes for in vitro and in vivo targeted computed tomography (CT) …

RETRACTED: Naringenin inhibits migration, invasion, induces apoptosis in human lung cancer cells and arrests tumour progression in vitro

X Shi, X Luo, T Chen, W Guo, C Liang… - Journal of cellular …, 2021 - Wiley Online Library
Lung cancer is one of the major cause for high‐death rate all over the world, due to
increased metastasize and difficulties in diagnosis. Naringenin is naturally occurring …

Recent advances in improved anticancer efficacies of camptothecin nano-formulations: A systematic review

M Ghanbari-Movahed, T Kaceli, A Mondal, MH Farzaei… - Biomedicines, 2021 - mdpi.com
Camptothecin (CPT), a natural plant alkaloid, has indicated potent antitumor activities via
targeting intracellular topoisomerase I. The promise that CPT holds in therapies is restricted …

CBX2 and EZH2 cooperatively promote the growth and metastasis of lung adenocarcinoma

FF Hu, H Chen, Y Duan, B Lan, CJ Liu, H Hu… - … Therapy-Nucleic Acids, 2022 - cell.com
The disruption of epigenetic regulation is common in tumors; the abnormal expression of
epigenetic factors leads to cancer occurrence and development. In this study, to investigate …

Camptothecin loaded nano-delivery systems in the cancer therapeutic domains: A critical examination of the literature

MK Alshammari, MM Alshehri, AM Alshehri… - Journal of Drug Delivery …, 2023 - Elsevier
For over a century, modern therapy has been at battle with malignancy, with no apparent
victory in sight. Cancer therapies have come a long way, but they still need to be more …

Naringenin inhibits migration of lung cancer cells via the inhibition of matrix metalloproteinases-2 and-9

HL Chang, YM Chang, SC Lai… - Experimental and …, 2017 - spandidos-publications.com
Lung cancer is among the most common causes of cancer‑related mortality. It has a high
mortality rate and resistance to chemotherapy due to its high metastatic potential …

Molecular mechanisms of action of naringenin in chronic airway diseases

LH Chin, CM Hon, DK Chellappan, J Chellian… - European journal of …, 2020 - Elsevier
Chronic airway inflammatory diseases are characterized by persistent proinflammatory
responses in the respiratory tract. Although, several treatment strategies are currently …