Exploring the mechanism of action of licorice in the treatment of COVID-19 through bioinformatics analysis and molecular dynamics simulation

JF Cao, Y Gong, M Wu, X Yang, L Xiong… - Frontiers in …, 2022 - frontiersin.org
Purpose: The rapid worldwide spread of Corona Virus Disease 2019 (COVID-19) has
become not only a global challenge, but also a lack of effective clinical treatments. Studies …

HLA‐DRA Gene Polymorphisms Are Associated with Graves' Disease as an Autoimmune Thyroid Disease

P Du, J Zhu, Q Yao, T Cai, J Xu, Y Fang… - BioMed Research …, 2022 - Wiley Online Library
Background. Autoimmune thyroid disease (AITD), one of the most prevalent organ‐specific
autoimmune diseases, mainly includes Graves' disease (GD) and Hashimoto's thyroiditis …

The role of high mobility group box 1 (HMGB1) in neurodegeneration: a systematic review

FZ Ikram, A Arulsamy, T Retinasamy… - Current …, 2022 - benthamdirect.com
Background: High mobility group box 1 (HMGB1) protein is a damage-associated molecular
pattern (DAMP) that plays an important role in the repair and regeneration of tissue injury. It …

Rs205764 and rs547311 in linc00513 may influence treatment responses in multiple sclerosis patients: A pharmacogenomics Egyptian study

NS Amin, MK Abd El-Aziz, M Hamed… - Frontiers in …, 2023 - frontiersin.org
Background Multiple sclerosis (MS) is characterized by a complex etiology that is reflected in
the lack of consistently predictable treatment responses across patients of seemingly similar …

Identification of key pathways and genes in dementia via integrated bioinformatics analysis

B Vastrad, C Vastrad - bioRxiv, 2021 - biorxiv.org
To provide a better understanding of dementia at the molecular level, this study aimed to
identify the genes and key pathways associated with dementia by using integrated …

Identification of key genes and signaling pathway in the pathogenesis of Huntington's disease via bioinformatics and next generation sequencing data analysis

BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org
Huntington's disease (HD) is the primary cause of progressive motor deficits, psychiatric
symptoms, and cognitive impairment. The exact molecular mechanisms of HD pathogenesis …

Screening of the Key Genes and Signaling Pathways for Schizophrenia Using Bioinformatics and Next Generation Sequencing Data Analysis

B Vastrad, C Vastrad - bioRxiv, 2023 - biorxiv.org
Schizophrenia is thought to be the most prevalent chronic psychiatric disorder. Numerous
proteins have been identified that are associated with the occurrence and development of …

Screening of the key genes and signaling pathways for schizophrenia using bioinformatics and next generation sequencing data analysis

I Kotturshetti, B Vastrad, V Kori, C Vastrad… - Italian Journal of …, 2024 - italjmed.org
Schizophrenia is thought to be the most prevalent chronic psychiatric disorder. Researchers
have identified numerous proteins associated with the occurrence and development of …

[PDF][PDF] Estimation of Genetic Correlation Between Rheumatoid Arthritis and Multiple Sclerosis Using Summary Statistics from Genome-Wide Association Studies.

RO Öztornacı - Journal of Clinical Practice & Research, 2023 - jag.journalagent.com
Objective: Genome-wide association studies (GWAS) have revolutionized our
understanding of the genetic basis of diseases by examining millions of genetic variants …

[PDF][PDF] Genotyping of FOXO3a gene polymorphism rs13217795 (C> T) in asthmatic Iraqi patients

TM Juda, SB Mohammed, AJ Al-Aaraji… - Journal of Health … - academia.edu
Background: Asthma is a chronic inflammatory process that affects the airways of the lung. It
has a greater impact on public health. It is a polygenic disease, many factors play a role …