Primary aldosteronism (PA) is a common cause of secondary hypertension. Recent
technological advances in genetic analysis have provided a better understanding of the …

Abstract Purpose of the Review Primary aldosteronism (PA) is the leading cause of
secondary hypertension, accounting for over 10% of patients with high blood pressure. It is …

Context Results of previous studies demonstrated clear racial differences in the prevalence
of somatic mutations among patients with aldosterone-producing adenoma (APA). For …

Objective: Prediction models have been developed to predict either unilateral or bilateral
primary aldosteronism, and these have not been validated externally. We aimed to develop …

Abstract Context and Objective Posture-responsive and posture-unresponsive aldosterone-
producing adenomas (APAs) account for approximately 40% and 60% of APAs, respectively …

Primary aldosteronism (PA) is the most common form of secondary hypertension, with a
prevalence of 5–10% among patients with hypertension. PA is mainly classified into two …

Primary aldosteronism (PA) is characterized by autonomous aldosterone production by
renin-independent mechanisms and is most commonly sporadic. While 60–70% of sporadic …

Background Adrenal tumors are found in up to 40% of patients with multiple endocrine
neoplasia type 1 (MEN1). However, adrenocortical carcinomas (ACC) and primary …

For the last seven decades, primary aldosteronism (PA) has been gradually recognized as a
leading cause of secondary hypertension harboring increased risks of cardiovascular …

Recent development of genetic analysis has revealed the molecular characteristics of
aldosterone-producing adrenocortical lesions, including gene mutations of KCNJ5, ATP1A1 …