Current advances for bone regeneration based on tissue engineering strategies

R Shi, Y Huang, C Ma, C Wu, W Tian - Frontiers of medicine, 2019 - Springer
Bone tissue engineering (BTE) is a rapidly developing strategy for repairing critical-sized
bone defects to address the unmet need for bone augmentation and skeletal repair. Effective …

Pharmacological advances in anti‐retroviral therapy for human immunodeficiency virus‐1 infection: A comprehensive review

N Azzman, MSA Gill, SS Hassan… - Reviews in Medical …, 2024 - Wiley Online Library
The discovery of anti‐retroviral (ARV) drugs over the past 36 years has introduced various
classes, including nucleoside/nucleotide reverse transcriptase inhibitors, non‐nucleoside …

Monomer sequence in PLGA microparticles: Effects on acidic microclimates and in vivo inflammatory response

MA Washington, SC Balmert, MV Fedorchak, SR Little… - Acta Biomaterialia, 2018 - Elsevier
Controlling the backbone architecture of poly (lactic-co-glycolic acid) s (PLGAs) is
demonstrated to have a strong influence on the production and release of acidic …

Synthesis and characterization of a long-acting emtricitabine prodrug nanoformulation

IM Ibrahim, AN Bade, Z Lin, D Soni… - International journal …, 2019 - Taylor & Francis
Purpose A palmitoylated prodrug of emtricitabine (FTC) was synthesized to extend the
drug's half-life, antiretroviral activities and biodistribution. Methods A modified FTC prodrug …

Preparation and evaluation of amphipathic lipopeptide‐loaded PLGA microspheres as sustained‐release system for AIDS prevention

H Jin, H Chong, Y Zhu, M Zhang, X Li… - Engineering in Life …, 2020 - Wiley Online Library
At present, AIDS drugs are typical inhibitors that cannot achieve permanent effects.
Therefore, the research of blocking HIV infection is essential. Especially for people in the …

Magnetically triggered release of biologics

OL Lanier, AG Monsalve… - International …, 2019 - journals.sagepub.com
The development of platforms for the controlled release of therapeutic molecules remains a
crucial research focus, as controlled release reduces the frequency of administration …

Human immunodeficiency virus infection challenges: Current therapeutic limitations and strategies for improved management through long‐acting injectable …

Tanushree, A Sharma, Monika… - Reviews in Medical …, 2024 - Wiley Online Library
HIV infection has been a severe global health burden, with millions living with the virus and
continuing new infections each year. Antiretroviral therapy can effectively suppress HIV …

Novel Delivery Systems for Oral Administration of Enfuvirtide: New Treatment Options for HIV/AIDS

H Pang, Z Qu, V Kumar, Y Wang, Y Wu… - Advanced …, 2024 - Wiley Online Library
Abstract Enfuvirtide (T‐20) is a synthetic peptide fusion inhibitor for the human
immunodeficiency virus (HIV), which causes acquired immunodeficiency syndrome (AIDS) …

Evaluation of the therapeutic properties of mastoparan-and sifuvirtide-derivative antimicrobial peptides using chemical structure-function relationship-in vivo and in …

S Avram, M Mernea, F Borcan… - Current Drug …, 2016 - ingentaconnect.com
Antimicrobial peptides, also called body defense peptides, are chemical structures widely
distributed across the animal and vegetal kingdoms that have a fundamental role as part of …

The Impact of Monomer Sequence and Stereochemistry on the Bulk Properties of Repeating Sequence Poly(Lactic-co-Glycolic Acid) Matrices

MA Washington - 2017 - search.proquest.com
Poly (lactic-co-glycolic acid)(PLGA)-based biodegradable materials have attracted
considerable interest in the field of bioengineering due to their biocompatibility, FDA …