[HTML][HTML] Besifloxacin liposomes with positively charged additives for an improved topical ocular delivery

GA Dos Santos, R Ferreira-Nunes, LF Dalmolin… - Scientific Reports, 2020 - nature.com
Topical ophthalmic antibiotics show low efficacy due to the well-known physiological
defense mechanisms of the eye, which prevents the penetration of exogenous substances …

[HTML][HTML] Compatibility and stability studies involving polymers used in fused deposition modeling 3D printing of medicines

IA Silva, AL Lima, T Gratieri, GM Gelfuso… - Journal of …, 2022 - Elsevier
One of the challenges in developing three-dimensional printed medicines is related to their
stability due to the manufacturing conditions involving high temperatures. This work …

Inkjet deposition of itraconazole onto poly (glycolic acid) microneedle arrays

RD Boehm, P Jaipan, SA Skoog, S Stafslien… - …, 2016 - pubs.aip.org
Poly (glycolic acid) microneedle arrays were fabricated using a drawing lithography process;
these arrays were modified with a drug release agent and an antifungal agent by …

Use of mixture design in drug-excipient compatibility determinations: Thymol nanoparticles case study

FQ Pires, T Angelo, JKR Silva, LCL Sá-Barreto… - … of pharmaceutical and …, 2017 - Elsevier
The objective of this work was to access thymol-excipient compatibility using an alternative
protocol of mixture design subsidizing the development of nanostructures lipid carriers …

Solid effervescent formulations as new approach for topical minoxidil delivery

MN Pereira, HL Schulte, N Duarte, EM Lima… - European journal of …, 2017 - Elsevier
Currently marketed minoxidil formulations present inconveniences that range from a grease
hard aspect they leave on the hair to more serious adverse reactions as scalp dryness and …

[HTML][HTML] Fabrication and optimization of itraconazole-loaded zein-based nanoparticles in coated capsules as a promising colon-targeting approach pursuing …

S Adel, RH Fahmy, I Elsayed, MI Mohamed… - Drug Delivery and …, 2023 - Springer
Abstract Itraconazole (ITZ), a broad-spectrum antifungal drug, was formulated into colon-
targeting system aiming to treat opportunistic colonic fungal infections that commonly infect …

Hot melt extrudates formulated using design space: one simple process for both palatability and dissolution rate improvement

LFB Malaquias, HL Schulte, JA Chaker, K Karan… - Journal of …, 2018 - Elsevier
This work aimed at obtaining an optimized itraconazole (ITZ) solid oral formulation in terms
of palatability and dissolution rate by combining different polymers using hot melt extrusion …

Melt crystallization and thermal degradation profile of the antichagasic drug nifurtimox

IP Gross, AL Lima, GR Bedogni, L Sa-Barreto… - … of Pharmaceutical and …, 2024 - Elsevier
Despite nifurtimox (NFX) being a traditional drug for treating Chagas disease, some of its
physicochemical properties are still unknown, especially its thermal behavior, which brings …

[图书][B] Nano-and microscale drug delivery systems: Design and fabrication

AM Grumezescu - 2017 - books.google.com
Nano-and Microscale Drug Delivery Systems: Design and Fabrication presents the
developments that have taken place in recent years in the field of micro-and nanoscale drug …

Mixture design applied in compatibility studies of catechin and lipid compounds

R Ferreira-Nunes, T Gratieri, GM Gelfuso… - … of pharmaceutical and …, 2018 - Elsevier
The aim of this work was to evaluate the compatibility of (+)-catechin (CA) and excipients
commonly used to prepare micro and nanoemulsions using thermal analysis along with …