[HTML][HTML] Besifloxacin liposomes with positively charged additives for an improved topical ocular delivery
GA Dos Santos, R Ferreira-Nunes, LF Dalmolin… - Scientific Reports, 2020 - nature.com
Topical ophthalmic antibiotics show low efficacy due to the well-known physiological
defense mechanisms of the eye, which prevents the penetration of exogenous substances …
defense mechanisms of the eye, which prevents the penetration of exogenous substances …
[HTML][HTML] Compatibility and stability studies involving polymers used in fused deposition modeling 3D printing of medicines
One of the challenges in developing three-dimensional printed medicines is related to their
stability due to the manufacturing conditions involving high temperatures. This work …
stability due to the manufacturing conditions involving high temperatures. This work …
Inkjet deposition of itraconazole onto poly (glycolic acid) microneedle arrays
RD Boehm, P Jaipan, SA Skoog, S Stafslien… - …, 2016 - pubs.aip.org
Poly (glycolic acid) microneedle arrays were fabricated using a drawing lithography process;
these arrays were modified with a drug release agent and an antifungal agent by …
these arrays were modified with a drug release agent and an antifungal agent by …
Use of mixture design in drug-excipient compatibility determinations: Thymol nanoparticles case study
FQ Pires, T Angelo, JKR Silva, LCL Sá-Barreto… - … of pharmaceutical and …, 2017 - Elsevier
The objective of this work was to access thymol-excipient compatibility using an alternative
protocol of mixture design subsidizing the development of nanostructures lipid carriers …
protocol of mixture design subsidizing the development of nanostructures lipid carriers …
Solid effervescent formulations as new approach for topical minoxidil delivery
Currently marketed minoxidil formulations present inconveniences that range from a grease
hard aspect they leave on the hair to more serious adverse reactions as scalp dryness and …
hard aspect they leave on the hair to more serious adverse reactions as scalp dryness and …
[HTML][HTML] Fabrication and optimization of itraconazole-loaded zein-based nanoparticles in coated capsules as a promising colon-targeting approach pursuing …
Abstract Itraconazole (ITZ), a broad-spectrum antifungal drug, was formulated into colon-
targeting system aiming to treat opportunistic colonic fungal infections that commonly infect …
targeting system aiming to treat opportunistic colonic fungal infections that commonly infect …
Hot melt extrudates formulated using design space: one simple process for both palatability and dissolution rate improvement
LFB Malaquias, HL Schulte, JA Chaker, K Karan… - Journal of …, 2018 - Elsevier
This work aimed at obtaining an optimized itraconazole (ITZ) solid oral formulation in terms
of palatability and dissolution rate by combining different polymers using hot melt extrusion …
of palatability and dissolution rate by combining different polymers using hot melt extrusion …
Melt crystallization and thermal degradation profile of the antichagasic drug nifurtimox
Despite nifurtimox (NFX) being a traditional drug for treating Chagas disease, some of its
physicochemical properties are still unknown, especially its thermal behavior, which brings …
physicochemical properties are still unknown, especially its thermal behavior, which brings …
[图书][B] Nano-and microscale drug delivery systems: Design and fabrication
AM Grumezescu - 2017 - books.google.com
Nano-and Microscale Drug Delivery Systems: Design and Fabrication presents the
developments that have taken place in recent years in the field of micro-and nanoscale drug …
developments that have taken place in recent years in the field of micro-and nanoscale drug …
Mixture design applied in compatibility studies of catechin and lipid compounds
R Ferreira-Nunes, T Gratieri, GM Gelfuso… - … of pharmaceutical and …, 2018 - Elsevier
The aim of this work was to evaluate the compatibility of (+)-catechin (CA) and excipients
commonly used to prepare micro and nanoemulsions using thermal analysis along with …
commonly used to prepare micro and nanoemulsions using thermal analysis along with …