Wake-up stroke and stroke of unknown onset: a critical review

A Wouters, R Lemmens, P Dupont, V Thijs - Frontiers in neurology, 2014 - frontiersin.org
Patients, who wake up with an ischemic stroke, account for a large number of the total stroke
population, due to circadian morning predominance of stroke. Currently, this subset of …

What to do with wake-up stroke

MN Rubin, KM Barrett - The Neurohospitalist, 2015 - journals.sagepub.com
Wake-up stroke, defined as the situation where a patient awakens with stroke symptoms that
were not present prior to falling asleep, represents roughly 1 in 5 acute ischemic strokes and …

Treatment concepts for wake-up stroke and stroke with unknown time of symptom onset

G Thomalla, C Gerloff - Stroke, 2015 - Am Heart Assoc
While the routine use of MRI as first line diagnostic tool in stroke imaging in the acute setting
is still restricted to large stroke centers, multiparametric CT is more widely available …

Reperfusion therapy in unclear-onset stroke based on MRI evaluation (RESTORE) a prospective multicenter study

DW Kang, SI Sohn, KS Hong, KH Yu, YH Hwang… - stroke, 2012 - Am Heart Assoc
Background and Purpose—Unclear-onset strokes are generally excluded from time-based
thrombolytic therapy. We examined the safety and feasibility of magnetic resonance imaging …

Wake-up or unclear-onset strokes: are they waking up to the world of thrombolysis therapy?

DW Kang, JY Kwon, SU Kwon… - International Journal of …, 2012 - journals.sagepub.com
Wake-up or unclear-onset strokes occur in up to one-fourth of patients with ischemic stroke.
Although stroke severity and clinical outcomes appear to be poorer in wake-up strokes than …

Clinical outcomes of patients with acute minor stroke receiving rescue IA therapy following early neurological deterioration

JT Kim, SH Heo, W Yoon, KH Choi, MS Park… - Journal of …, 2016 - jnis.bmj.com
Background Patients presenting with minor ischemic stroke frequently have early
neurological deterioration (END) and poor final outcome. The optimal management of …

Wake-up stroke: imaging-based diagnosis and recanalization therapy

YL Zhang, JF Zhang, XX Wang, Y Wang… - Journal of …, 2021 - Springer
Wake-up stroke (WUS) is a subgroup of ischemic stroke in which patients show no
abnormality before sleep while wake up with neurological deficits. In addition to the …

Various blood glucose parameters that indicate hyperglycemia after intravenous thrombolysis in acute ischemic stroke could predict worse outcome

DS Yoo, J Chang, JT Kim, MJ Choi, J Choi, KH Choi… - PloS one, 2014 - journals.plos.org
Background Hyperglycemia is common after stroke, and it is well known to worsen its
outcome. However, it is important to consider that blood glucose (BG) levels can undergo …

Lipoic acid use and functional outcomes after thrombolysis in patients with acute ischemic stroke and diabetes

KH Choi, MS Park, JT Kim, HS Kim, JH Kim, TS Nam… - PLoS …, 2016 - journals.plos.org
Background Alpha-lipoic acid (aLA) is a strong antioxidant commonly used for treating
diabetic polyneuropathy. Previously, we demonstrated the neurorestorative effects of aLA …

Endovascular therapy of wake-up strokes in the modern era of stent retriever thrombectomy

M Mokin, P Kan, S Sivakanthan… - Journal of …, 2016 - jnis.bmj.com
Background Endovascular treatment of wake-up strokes (WUS) has been previously
described, mostly with the use of pharmacological thrombolysis or first generation …